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TNF-alpha Monoclonal Antibody, Clone: MP6-XT3, Invitrogen™ DFS Item


TNF-alpha Antibody (MP6-XT3), AMC3812, from Invitrogen™. Species Reactivity: Mouse; Applications: Functional Assay, Neutralization.

Manufacturer: life technologies  LSAMC3812

Catalog No. AMC3812

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Description & Specifications

Specifications

Cross Reactivity Mouse
Monoclonal or Polyclonal Monoclonal
Immunogen Recombinant TNF-alpha
Storage Requirements Store at -20°C
Clone MP6-XT3
Isotype IgG1, κ
Conjugate Unlabeled
Host Species Rat
Formulation 500μg of purified antibody in PBS with no preservative; pH 7.2.
Format Purified
Antigen TNF-alpha
Gene ID (Entrez) 21926
Gene Accession No. P06804
Primary or Secondary Primary

TNF-alpha Antibody (MP6-XT3), AMC3812, from Invitrogen™. Species Reactivity: Mouse; Applications: Functional Assay, Neutralization.

This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
Host Species: Rat
Cross Reactivity: Mouse
Isotype: IgG1, κ
Clone: MP6-XT3
Immunogen: Recombinant TNF-alpha
Formulation: 500μg purified antibody (1mg/mL) in PBS and no preservative; pH 7.2
Synonyms: APC1 protein, TNF superfamily, member 2, TNF, macrophage-derived, TNF, monocyte-derived, TNF-a, cachectin, tumor necrosis factor alpha, tumor necrosis factor ligand superfamily member 2, tumor necrosis factor-alpha, TNFA
Uniprot Accession: P06804
Entrez GeneID: 21926
Gene Symbol: TNF
This product detects TNF-alpha in Mouse samples. This product has been successfully used in Functional Assay and Neutralization procedures. The immunogen is Recombinant TNF-alpha.

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