TNF-alpha Monoclonal Antibody, Clone: MP6-XT3, Invitrogen™
TNF-alpha Antibody (MP6-XT3), AMC3812, from Invitrogen™. Species Reactivity: Mouse; Applications: Functional Assay, Neutralization.
Manufacturer: Life Technologies LSAMC3812
TNF-alpha Antibody (MP6-XT3), AMC3812, from Invitrogen™. Species Reactivity: Mouse; Applications: Functional Assay, Neutralization.This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
Host Species: Rat
Cross Reactivity: Mouse
Isotype: IgG1, κ
Immunogen: Recombinant TNF-alpha
Formulation: 500μg purified antibody (1mg/mL) in PBS and no preservative; pH 7.2
Synonyms: APC1 protein, TNF superfamily, member 2, TNF, macrophage-derived, TNF, monocyte-derived, TNF-a, cachectin, tumor necrosis factor alpha, tumor necrosis factor ligand superfamily member 2, tumor necrosis factor-alpha, TNFA
Uniprot Accession: P06804
Entrez GeneID: 21926
Gene Symbol: TNF
This product detects TNF-alpha in Mouse samples. This product has been successfully used in Functional Assay and Neutralization procedures. The immunogen is Recombinant TNF-alpha.
|500μg of purified antibody in PBS with no preservative; pH 7.2.|
|Store at -20°C|