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MilliporeSigma™ anti-TCR beta chain, PerCP-Cy5.5, Clone: H57-597,
Armenian Hamster Monoclonal Antibody
$489.54 - $489.54
Specifications
Antigen | TCR beta chain |
---|---|
Clone | H57-597 |
Applications | Flow Cytometry |
Classification | Monoclonal |
Conjugate | PerCP-Cyanine5.5 |
Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
MABF1457MI
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MilliporeSigma™
MABF1457 |
100 μg |
Each for $489.54
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Description
Specifically detects TCR beta chain Clone: H57-597 in Mouse samples, and it is validated for Flow Cytometry
The H57-597 antibody is specific for the beta chain of the mouse T cell Receptor (TCR). This cell surface protein combines with a second protein chain (alpha chain) to form the alpha-beta TCR that is expressed by NK1.1+ thymocytes, NKT cells, and the majority of peripheral T cells. A small number of T cells may express an alternative heteromer of gamma/delta protein chains, known as the g/d TCR. These receptors participate in a complex with CD3, and with the co-receptors CD4 or CD8, to recognize and respond to antigens bound to MHC molecules on antigen-presenting cells. Such interactions promote T cell receptor signaling (T cell activation) and can result in a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death.The H57-597 antibody is used as a phenotypic marker for T cells expressing the alpha-beta TCR. It is also widely used to cross-link surface TCR and thereby mimic TCR-mediated cell activation or induction of apoptosis. The antibody does not cross-react with cells expressing the g/d TCR.Specifications
TCR beta chain | |
Flow Cytometry | |
PerCP-Cyanine5.5 | |
Armenian Hamster | |
Inflammation, Immunology | |
Purified Armenian Hamster monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1%Â gelatin, pH 7.2. | |
Ptcra | |
IgG | |
Purified by size-exclusion chromatography |
H57-597 | |
Monoclonal | |
Purified | |
RUO | |
Mouse | |
P0C6B2 | |
Proprietary immunogen | |
Primary | |
2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze |
For Research Use Only