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anti-Superoxide Dismutase 1 Polyclonal, Thermo Scientific™

Superoxide Dismutase 1 Polyclonal Ab PA1-18276 from Thermo Scientific™ detects Superoxide Dismutase 1 in Hu samples, and is validated for IHC (Paraffin, Frozen) and WB

$480.90 - $509.25

Specifications

Antigen Superoxide Dismutase 1
Cross Reactivity Mouse
Cross Reactivity Rat
Format Serum
Host Species Rabbit
View More Specs
Products
Catalog Number Mfr. No. Conjugate Quantity Price Quantity    

01-670-527

 
pierce biotechnology inc
PA118274
Unlabeled 100μL Each for $480.90

01-670-528

 
pierce biotechnology inc
PA118275
Unlabeled 100μL Each for $494.55

01-670-529

 
pierce biotechnology inc
PA118276
Unlabeled 100μL Each for $509.25
Description & Specifications

Specifications

Antigen Superoxide Dismutase 1
Cross Reactivity Mouse
Cross Reactivity Rat
Format Serum
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues A(24) S G E P V V L S G Q I T(36) of mouse superoxide dismutase (SOD1).
Isotype IgG
Monoclonal or Polyclonal Polyclonal
Primary or Secondary Primary
Storage Requirements Avoid Freeze/Thaw Cycles

Superoxide Dismutase 1 Polyclonal Ab PA1-18276 from Thermo Scientific™ detects Superoxide Dismutase 1 in Hu samples, and is validated for IHC (Paraffin, Frozen) and WB

Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O2) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase. Several classes of SOD have been identified. These include intracellular copper, zinc SOD (Cu, Zn-SOD/SOD-1), mitochondrial manganese SOD (Mn-SOD/SOD-2) and extracellular Cu, Zn-SOD (EC-SOD/SOD-3) (1). SOD1 is found in all eukaryotic species as a homodimeric 32 kDa enzyme containing one each of Cu and Zn ion per subunit (2). The manganese containing 80 kDa tetrameric enzyme SOD2, is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain (3). SOD3 is a heparin-binding multimer of disulfide-linked dimers, primarily expressed in human lungs, vessel walls and airways (4). SOD4 is a copper chaperone for superoxide dismutase (CCS), which specifically delivers Cu to copper/zinc superoxide dismutase. CCS may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor
Host Species: Rabbit
Cross Reactivity: Human
Isotype: IgG
Immunogen: Synthetic peptide corresponding to residues H(121) E K A D D L G K G G N E E S T K T G(139) of human superoxide dismutase (SOD1).
Formulation: 100μL unpurified Antibody in whole serum, with no preservative;
Synonyms: SOD1, ALS, ALS1, Cu/Zn superoxide dismutase, Homodimer, Indophenoloxidase A, IPOA
Uniprot Accession: P00441
Gene Symbol: SOD1
Entrez GeneID: 6647
PA1-18276 detects Superoxide Dismutase 1 in Human samples. PA1-18276 has been successfully used in Immunohistochemistry (Paraffin, Frozen) and Western Blot procedures. PA1-18276 The immunogen is Synthetic peptide corresponding to residues H(121) E K A D D L G K G G N E E S T K T G(139) of human superoxide dismutase (SOD1)..