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SPP1 Monoclonal Antibody, Clone: 7C5H12, Invitrogen™

SPP1 Antibody (7C5H12), MA5-17180, from Invitrogen™. Species Reactivity: Human; Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot.

Manufacturer:  Pierce Biotechnology Inc MA517180

Catalog No. PIMA517180


 

Specifications

Description

SPP1 Antibody (7C5H12), MA5-17180, from Invitrogen. Species Reactivity: Human; Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot.

The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene.
Host Species: Mouse
Cross Reactivity: Human
Isotype: IgG1
Clone: 7C5H12
Immunogen: Purified recombinant fragment of human SPP1 (amino acids: 167-314) expressed in E. Coli.
Formulation: 100 ug purified antibody (1mg/mL) in PBS with 0.5% proprietary stabilizer and 0.05% sodium azide
Uniprot Accession: P10451
Entrez GeneID: 6696
Gene Symbol: SPP1
MA5-17180 targets SPP1 in ICC, IHC, IF and WB applications and shows reactivity with Human samples. The MA5-17180 immunogen is purified recombinant fragment of human SPP1 (amino acids: 167-314) expressed in E. Coli. MA5-17180 detects SPP1 which has a predicted molecular weight of approximately 35.4kDa.
References:
Test: ICC, Dilution: 1:500, Species: Rb, Reference: Restoration of critical-size defects in the rabbit mandible using porous nanohydroxyapatite-polyamide scaffolds. (Jun 2012) Tissue Eng Part A, Vol: 18, 11-12, 1239-52, Guo J,Meng Z,Chen G,Xie D,Chen Y,Wang H,Tang W,Liu L,Jing W,Long J,Guo W,Tian W; Pubmed ID: 22320360
Description & Specifications

Specifications

SPP1
7C5H12
100μg purified antibody (1mg/mL) in PBS with 0.5% proprietary stabilizer and 0.05% sodium azide
Purified
Murine
IgG1
avoiding freeze/thaw cycles.
Monoclonal
Human
Immunocytochemistry,Immunofluorescence,Immunohistochemistry,Western Blot
Unlabeled
P10451
SPP1
Purified recombinant fragment of human SPP1 (amino acids: 167-314) expressed in E. Coli.
100μg
Primary
6696
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Promotions

  • Purchase any three Invitrogen™ Antibodies and receive a fourth antibody at no additional cost. This is an NLSU exclusive offer. You must apply and qualify for the program to be eligible.

    06/30/18