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SPP1 Monoclonal Antibody, Clone: 7C5H12, Invitrogen™


SPP1 Antibody (7C5H12), MA5-17180, from Invitrogen™. Species Reactivity: Human; Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot.

Manufacturer: pierce biotechnology inc  MA517180

Catalog No. PIMA517180

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Description & Specifications

Specifications

Antigen SPP1
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry
Applications Western Blot
Clone 7C5H12
Conjugate Unlabeled
Cross Reactivity Human
Format Purified
Formulation 100μg purified antibody (1mg/mL) in PBS with 0.5% proprietary stabilizer and 0.05% sodium azide
Gene Accession No. P10451
Gene Symbols SPP1
Host Species Mouse
Immunogen Purified recombinant fragment of human SPP1 (amino acids: 167-314) expressed in E. Coli.
Isotype IgG1
Quantity 100μg
Species Reactivity Human
Storage Requirements avoiding freeze/thaw cycles.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Gene ID (Entrez) 6696

SPP1 Antibody (7C5H12), MA5-17180, from Invitrogen. Species Reactivity: Human; Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot.

The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene.
Host Species: Mouse
Cross Reactivity: Human
Isotype: IgG1
Clone: 7C5H12
Immunogen: Purified recombinant fragment of human SPP1 (amino acids: 167-314) expressed in E. Coli.
Formulation: 100 ug purified antibody (1mg/mL) in PBS with 0.5% proprietary stabilizer and 0.05% sodium azide
Uniprot Accession: P10451
Entrez GeneID: 6696
Gene Symbol: SPP1
MA5-17180 targets SPP1 in ICC, IHC, IF and WB applications and shows reactivity with Human samples. The MA5-17180 immunogen is purified recombinant fragment of human SPP1 (amino acids: 167-314) expressed in E. Coli. MA5-17180 detects SPP1 which has a predicted molecular weight of approximately 35.4kDa.
References:
Test: ICC, Dilution: 1:500, Species: Rb, Reference: Restoration of critical-size defects in the rabbit mandible using porous nanohydroxyapatite-polyamide scaffolds. (Jun 2012) Tissue Eng Part A, Vol: 18, 11-12, 1239-52, Guo J,Meng Z,Chen G,Xie D,Chen Y,Wang H,Tang W,Liu L,Jing W,Long J,Guo W,Tian W; Pubmed ID: 22320360