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anti-Sphingosine Kinase 2 Polyclonal, Thermo Scientific™

Sphingosine Kinase 2 Polyclonal Ab PA1-12720 from Thermo Scientific™ specifically detects Sphingosine Kinase 2 in Hu, Ms and Rt samples, and it is validated for ELISA and WB

$579.60 - $672.00

Specifications

Antigen Sphingosine Kinase 2
Cross Reactivity Human
Format Purified
Host Species Rabbit
Immunogen Synthetic peptide corresponding to the N-terminal extension of Sphingosine Kinase 2-L.
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Products
Catalog Number Mfr. No. Conjugate Quantity Price Quantity    

01-674-850

 
pierce biotechnology inc
PA112720
Unlabeled 10 Miniblots Each for $672.00

01-675-852

 
pierce biotechnology inc
PA112872
Unlabeled 10 Miniblots Each for $579.60
Description & Specifications

Specifications

Antigen Sphingosine Kinase 2
Cross Reactivity Human
Format Purified
Host Species Rabbit
Immunogen Synthetic peptide corresponding to the N-terminal extension of Sphingosine Kinase 2-L.
Isotype IgG
Monoclonal or Polyclonal Polyclonal
Primary or Secondary Primary
Storage Requirements Avoid Freeze/Thaw Cycles

Sphingosine Kinase 2 Polyclonal Ab PA1-12720 from Thermo Scientific™ specifically detects Sphingosine Kinase 2 in Hu, Ms and Rt samples, and it is validated for ELISA and WB

Sphingosine Kinase 2 (Sphk2) catalyzes the phosphorylation of sphingosine to sphingosine 1 phosphate (S1P), an important signaling molecule with intra- and extracellular functions. Inside the cell S1P acts as a signaling molecule like other sphingolipid metabolites like ceramide and sphingosine. S1P has been implicated in regulating cell differentiation, calcium mobilization from intracellular stores, and apoptosis. The cell surface receptors for S1P are the EDG family of G protein-coupled receptors (S1P Receptors).These receptors couple to multiple G proteins (e.g. S1P1 couples to Gi whereas S1P2 and S1P3 couple to Gq, G13 in addition to Gi) and regulate a extremely wide range of cellular events including cell motility, survival, apoptosis, migration and cellcell interaction. Important roles for S1P have also been reported in regulation of cardiogenesis, vascular maturation, oocyte survival, immune cell trafficking, cells of the neuronal system and bone cells. S1P levels are regulated by the activity of Sphk (Sphk1 and Sphk2).
Host Species: Rabbit
Cross Reactivity: Human, Mouse, Rat
Isotype: IgG
Immunogen: Synthetic peptide corresponding to the C-terminal of Sphingosine Kinase 2.
Formulation: 10 Miniblots purified Antibody in PBS, with 0.08% sodium azide;
Synonyms: C76851, MGC102297
Uniprot Accession: Q8CI19, Q9EQX6, Q9NRA1
Gene Symbol: PDGFC
Entrez GeneID: 54635, 56034, 79429
PA1-12720 detects Sphingosine Kinase 2 in Human, Mouse and Rat samples. PA1-12720 has been successfully used in ELISA and Western Blot procedures. PA1-12720 The immunogen is Synthetic peptide corresponding to the C-terminal of Sphingosine Kinase 2..