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SERPINC1 (M02), Mouse anti-Human, Clone: 2B12, Abnova™

Mouse monoclonal antibody raised against a full-length recombinant SERPINC1.

Supplier:  Abnova Corporation H00000462M02

Catalog No. 89-016-230



Description

Description

The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency. [provided by RefSeq

Sequence: MYSNVIGTVTSGKRKVYLLSLLLIGFWDCVTCHGSPVDICTAEPRDIPMNPMCIYRSPEKKATEDEGSEQKIPEATNRRVWELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANRPFLVFIREVPLNTIIFMGRVANPCVK
Specifications

Specifications

SERPINC1
Monoclonal
Unconjugated
PBS with no preservative; pH 7.4
BC022309
SERPINC1
SERPINC1 (AAH22309.1, 1 a.a. ∼ 259 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
100 μg
Primary
Human
Antibody
IgG2b κ
ELISA, Western Blot
2B12
Mouse monoclonal antibody raised against a full length recombinant SERPINC1.
SERPINC1
AT3/ATIII/MGC22579
Mouse
Affinity chromatography
RUO
462
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Liquid
SDS
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