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ROC1 Polyclonal Antibody, Invitrogen™


ROC1 Antibody, PA5-16282, from Invitrogen™. Species Reactivity: Human, Mouse; Applications: Immunoprecipitation, Western Blot.

Manufacturer: pierce biotechnology inc  PA516282

Catalog No. PIPA516282

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Description & Specifications

Specifications

Formulation 500μL purified antibody (1mg/mL) in PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Applications Immunoprecipitation
Applications Western Blot
Gene Accession No. P62877, P62878
Gene Alias RING box protein 1, RING finger protein 75, RING-box protein 1, ZYP protein, regulator of cullins 1
Gene Symbols RBX1
Species Reactivity Human, Mouse
Storage Requirements Store at 4° C
Gene ID (Entrez) 56438, 9978
Host Species Rabbit
Immunogen A peptide corresponding to amino acid residue 97-108 (CPLDNREWEFQKYGH) from C-terminus of the human ROC1
Format Purified
Conjugate Unlabeled
Isotype IgG
Monoclonal or Polyclonal Polyclonal
Cross Reactivity Human
Cross Reactivity Mouse
Quantity 500μL
Primary or Secondary Primary
Antigen ROC1
Regulatory Status RUO

ROC1 Antibody, PA5-16282, from Invitrogen. Species Reactivity: Human, Mouse; Applications: Immunoprecipitation, Western Blot.

ROC1 and ROC2 are the two highly conserved RING finger proteins that are homologous to APC11, a subunit of the anaphase-promoting complex(APC). ROC1 and ROC2 commonly interact with all cullins while APC11 specifically interacts with APC2, a cullin-related APC subunit. ROC1 and APC11 immunocomplexes can catalyze isopeptide ligations to form polyubiquitin chains in an E1- and E2-dependent manner. ROC1 is thought to play a unique role in the ubiquitination reaction by heterodimerizing with cullin1 to catalyze ubiquitin polymerization.
Host Species: Rabbit
Cross Reactivity: Human, Mouse
Isotype: IgG
Immunogen: A peptide corresponding to amino acid residue 97-108 (CPLDNREWEFQKYGH) from C-terminus of the human ROC1
Formulation: 500μL purified antibody (1mg/mL) in PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Synonyms: RING box protein 1, RING finger protein 75, RING-box protein 1, ZYP protein, regulator of cullins 1
Uniprot Accession: P62877, P62878
Entrez GeneID: 56438, 9978
Gene Symbol: RBX1
PA5-16282 targets ROC1 in IP and WB applications and shows reactivity with Human and mouse samples. The PA5-16282 immunogen is a peptide corresponding to amino acid residue 97-108 (CPLDNREWEFQKYGH) from C-terminus of the human ROC1.