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anti-RIT1 Polyclonal, Thermo Scientific™

RIT1 Polyclonal antibody PA1-12571 from Thermo Scientific™ specifically detects RIT1 in Human samples, and it is validated for Western Blot

$395.85 - $395.85

Specifications

Antigen RIT1
Cross Reactivity Human
Format Purified
Host Species Rabbit
Immunogen His-tagged recombinant human Rit protein.
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Products
Catalog Number Mfr. No. Conjugate Quantity Price Quantity    

01-674-798

 
pierce biotechnology inc
PA112571
Unlabeled 100μg Each for $395.85
Description & Specifications

Specifications

Antigen RIT1
Cross Reactivity Human
Format Purified
Host Species Rabbit
Immunogen His-tagged recombinant human Rit protein.
Isotype IgG
Monoclonal or Polyclonal Polyclonal
Primary or Secondary Primary
Storage Requirements Avoid Freeze/Thaw Cycles

RIT1 Polyclonal antibody PA1-12571 from Thermo Scientific™ specifically detects RIT1 in Human samples, and it is validated for Western Blot

Rit and its neuron-specific homologue, Rin, define a recently discovered subfamily of Ras-related GTPases. Rit and Rin are membrane-associated in spite of the fact that they lack a CAAX box or similar C-terminal lipidation motif. Rit and Rin display 64% amino acid sequence identity and share a unique nine amino acid effector domain (DPTIEDAYK) that is 100% conserved between the murine and human proteins. Although the effector domain sequences of Rit and Rin are very similar to that of Ras, Rit and Rin have been shown to interact with the known Ras-binding proteins RalGDS, Rlf and AF-6, but not the Raf kinases, RIN1 or the p110 subunit of PI3 kinase. For this reason, it has been suggested that Rit and Rin may play important roles in the regulation of signaling pathways distinct from those controlled by Ras.
Host Species: Rabbit
Cross Reactivity: Human
Isotype: IgG
Immunogen: His-tagged recombinant human Rit protein.
Formulation: 100μg purified Antibody in PBS, with 0.08% sodium azide;
Synonyms: MGC125864, MGC125865, RIBB, RIT, ROC1
Uniprot Accession: Q92963
Gene Symbol: RIT1
Entrez GeneID: 6016
PA1-12571 detects RIT1 in Human samples. PA1-12571 has been successfully used in Western Blot procedures. PA1-12571 The immunogen is His-tagged recombinant human Rit protein..