PIN1 Chicken anti-Bovine, Chicken, Equine, Human, Mouse, Porcine, Rat, Polyclonal, Invitrogen™

Description

Peptidyl-prolyl cis/trans isomerases , such as PIN1, catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. PIN1 is the only PPIase that specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. PIN1-catalyzed conformational regulation has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, germ cell development, neuronal differentiation, and survival.