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NUMB Polyclonal Antibody, Invitrogen™


NUMB Antibody, PA1-16831, from Invitrogen™. Species Reactivity: Chicken, Human, Mouse; Applications: Immunocytochemistry, Immunofluorescence, Western Blot.

Manufacturer: pierce biotechnology inc  PA116831

Catalog No. APPA6831

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Description & Specifications

Specifications

Antigen NUMB
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Western Blot
Conjugate Unlabeled
Cross Reactivity Chicken
Cross Reactivity Human
Cross Reactivity Mouse
Format Purified
Formulation 100μL purified antibody (3.5mg/mL) in tris glycine with 0.15M NaCl and 0.05% sodium azide
Gene Accession No. P49757, Q9QZS3
Gene Alias Protein S171
Gene Symbols NUMB
Host Species Rabbit
Immunogen A synthetic peptide made to a C-terminal region of the murine numb protein sequence (between residues 600-653).
Isotype IgG
Quantity 100μL
Species Reactivity Chicken, Human, Mouse
Storage Requirements avoiding freeze/thaw cycles.
Primary or Secondary Primary
Monoclonal or Polyclonal Polyclonal
Gene ID (Entrez) 18222, 395639, 8650

NUMB Antibody, PA1-16831, from Invitrogen. Species Reactivity: Chicken, Human, Mouse; Applications: Immunocytochemistry, Immunofluorescence, Western Blot.

Numb is an evolutionarily conserved membrane-associated protein. It exists in four isoforms that differ in two functional domains: a phosphotyrosine-binding (PTB) domain and a proline-rich region (PRR). It plays a role in the control of cell fate decisions during development and antagonizes the actions of Notch. Numb proteins appear to control the self-renewal of all neural progenitor cells and could possibly play similar roles in stem-cell maintenance in other tissues.
Host Species: Rabbit
Cross Reactivity: Chicken, Human, Mouse
Isotype: IgG
Immunogen: A synthetic peptide made to a C-terminal region of the murine numb protein sequence (between residues 600-653).
Formulation: 100μL purified antibody (3.5mg/mL) in tris glycine with 0.15M NaCl and 0.05% sodium azide
Synonyms: Protein S171
Uniprot Accession: P49757, Q9QZS3
Entrez GeneID: 18222, 395639, 8650
Gene Symbol: NUMB
The target sequence has 90% sequence homology with rat.