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anti-Netrin 1 Polyclonal, Thermo Scientific™

Netrin 1 Polyclonal Ab PA1-12869 from Thermo Scientific™ specifically detects Netrin 1 in Bv, Feline, Hu, Ms, Nhp and Rt samples, and it is validated for WB

$564.90 - $564.90

Specifications

Antigen Netrin 1
Cross Reactivity Bovine
Cross Reactivity Feline
Cross Reactivity Human
Cross Reactivity Mouse
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Products
Catalog Number Mfr. No. Conjugate Quantity Price Quantity    

01-675-846

 
pierce biotechnology inc
PA112866
Unlabeled 25μg Each for $564.90

01-675-849

 
pierce biotechnology inc
PA112869
Unlabeled 100μg Each for $564.90
Description & Specifications

Specifications

Antigen Netrin 1
Cross Reactivity Bovine
Cross Reactivity Feline
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Non-human primate
Cross Reactivity Rat
Format Purified
Host Species Rabbit
Immunogen Synthetic peptide corresponding to human Netrin 1.
Isotype IgG
Monoclonal or Polyclonal Polyclonal
Primary or Secondary Primary
Storage Requirements Avoid Freeze/Thaw Cycles

Netrin 1 Polyclonal Ab PA1-12869 from Thermo Scientific™ specifically detects Netrin 1 in Bv, Feline, Hu, Ms, Nhp and Rt samples, and it is validated for WB

Netrin 1’s main receptor is DCC (deleted in colorectal cancer- a putative tumor suppressor gene whose expression is lost in numerous cancers). DCC belongs to the so-called family of dependence receptors. These receptors induce apoptosis when their ligand is absent, thus conferring a state of cellular dependence on Netrin 1 availability. The DCC/netrin-1 duo regulates neuron survival during nervous system development. The mechanism(s) by which Netrin 1/ DCC triggers cell death are still unknown. The localization of DCC to lipid rafts appears to be a prerequisite for its proapoptotic activity.
Host Species: Rabbit
Cross Reactivity: Bovine, Feline, Human, Mouse, Non-human primate, Rat
Isotype: IgG
Immunogen: Synthetic peptide corresponding to human Netrin 1.
Formulation: 100μg purified Antibody (1mg/mL) in PBS, with 0.08% sodium azide;
Synonyms: NTN1L
Uniprot Accession: O09118, O95631, Q924Z9
Gene Symbol: NTN1
Entrez GeneID: 101082606, 114523, 18208, 522767, 9423
PA1-12869 detects Netrin 1 in Bovine, Feline, Human, Mouse, Non-human primate and Rat samples. PA1-12869 has been successfully used in Western Blot procedures. PA1-12869 The immunogen is Synthetic peptide corresponding to human Netrin 1..