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anti-Myeloperoxidase Polyclonal, Thermo Scientific™

Myeloperoxidase Polyclonal Ab PA1-18308 from Thermo Scientific™ specifically detects Myeloperoxidase in Hu samples, and it is validated for IHC (Paraffin, Frozen) and WB

$522.90 - $522.90

Specifications

Antigen Myeloperoxidase
Cross Reactivity Human
Format Purified
Host Species Rabbit
Immunogen Myeloperoxidase isolated from human polymorphonuclear leucocytes.
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Products
Catalog Number Mfr. No. Conjugate Quantity Price Quantity    

01-670-561

 
pierce biotechnology inc
PA118308
Unlabeled 250μg Each for $522.90
Description & Specifications

Specifications

Antigen Myeloperoxidase
Cross Reactivity Human
Format Purified
Host Species Rabbit
Immunogen Myeloperoxidase isolated from human polymorphonuclear leucocytes.
Isotype IgG
Monoclonal or Polyclonal Polyclonal
Primary or Secondary Primary
Storage Requirements Avoid Freeze/Thaw Cycles

Myeloperoxidase Polyclonal Ab PA1-18308 from Thermo Scientific™ specifically detects Myeloperoxidase in Hu samples, and it is validated for IHC (Paraffin, Frozen) and WB

Myeloperoxidase is a hemoprotein that is abundantly expressed in neutrophils and secreted during their activation. Native Myeloperoxidase is represented as a covalently bound tetrameric complex of two glycosylated alpha chains (MW ∽59 - 64 kDa) and two unglycosylated beta chains (MW ∽14 kDa) with total MW ∽150 kDa and theoretical pI 9.2. Traditionally Myeloperoxidase was considered as a main target of anti-neutrophil cytoplasm antibodies (ANCA), the serological markers for certain systemic vasculities e.g. periarteriitis nodosa, microscopic polyarteriitis and pulmonary eosinophilic granulomatosis (Churg-Strauss syndrome). Low to moderate anti-Myeloperoxidase autoantibody levels are also reported in rheumatoid arthritis. Recently it was shown that Myeloperoxidase participates in the initiation and progression of cardiovascular disease. It possesses potent proinflammatory properties and may contribute directly to tissue injury. Now Myeloperoxidase is under consideration as one of the most promising cardiac markers.
Host Species: Rabbit
Cross Reactivity: Human
Isotype: IgG
Immunogen: Myeloperoxidase isolated from human polymorphonuclear leucocytes.
Formulation: 250μg purified Antibody (1mg/mL) no preservative;
Synonyms: MPO
Uniprot Accession: P05164
Gene Symbol: MPO
Entrez GeneID: 4353
PA1-18308 detects Myeloperoxidase in Human samples. PA1-18308 has been successfully used in Immunohistochemistry (Paraffin, Frozen) and Western Blot procedures. PA1-18308 The immunogen is Myeloperoxidase isolated from human polymorphonuclear leucocytes..