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anti-GnRH Polyclonal, Thermo Scientific™

GnRH Polyclonal antibody PA1-122 from Thermo Scientific™ specifically detects GnRH in Mouse samples, and it is validated for Immunohistochemistry (Frozen)

$480.90 - $480.90

Specifications

Antigen GnRH
Cross Reactivity Mouse
Format Purified
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues pyroE(22) H W S Y G L R P G-NH2(32) of mouse GnRH.
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PA1122

 
pierce biotechnology inc
PA1122
Unlabeled 100μg Each for $480.90
Description & Specifications

Specifications

Antigen GnRH
Cross Reactivity Mouse
Format Purified
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues pyroE(22) H W S Y G L R P G-NH2(32) of mouse GnRH.
Isotype IgG
Monoclonal or Polyclonal Polyclonal
Primary or Secondary Primary
Storage Requirements Avoid Freeze/Thaw Cycles

GnRH Polyclonal antibody PA1-122 from Thermo Scientific™ specifically detects GnRH in Mouse samples, and it is validated for Immunohistochemistry (Frozen)

Gonadotropin releasing hormone (GnRH), also known as luteinizing hormone releasing hormone (LHRH), is a key molecule in the regulation of reproduction in vertebrates. GnRH, a decapeptide, is produced by neurons in the medial basal hypothalamus (MBH) and secreted in a pulsatile manner into the cardiovascular system. The frequency and amplitude of GnRH pulses determine secretion of follicle stimulating hormone (FSH) and luteinizing hormone (LH) from the pituitary. Higher frequencies (greater than one pulse per hour) stimulate LH secretion while lower frequencies stimulate FSH secretion. The generation of GnRH pulses is effected by numerous stimuli, such as neural, hormonal and environmental. Therefore, behavioral and physiological conditions such as sleep, exercise, and stress can affect the GnRH pulses and cause a disruption of the normal cycle.   Recent studies show that GnRH also has a role in mediating cancer. GnRH has been shown to inhibit the growth of human uterine leiomyloma cells by suppressing proliferation and inducing apoptosis. GnRH analogs have been used to treat a wide variety of reproductive cancers, although the side effects of using such compounds are often quite severe.
Host Species: Rabbit
Cross Reactivity: Mouse
Isotype: IgG
Immunogen: Synthetic peptide corresponding to residues pyroE(22) H W S Y G L R P G-NH2(32) of mouse GnRH.
Formulation: 100μg purified Antibody (1mg/mL) in PBS, with 1mg/ml BSA and 0.05% sodium azide;
Synonyms: Gonadotropin Releasing Hormone, LHRH, Luteinizing Hormone Releasing Hormone
Uniprot Accession: P13562
Gene Symbol: Gnrh1
Entrez GeneID: 14714
PA1-122 detects GnRH in Mouse samples. PA1-122 has been successfully used in Immunohistochemistry (Frozen) procedures. PA1-122 The immunogen is Synthetic peptide corresponding to residues pyroE(22) H W S Y G L R P G-NH2(32) of mouse GnRH..