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anti-TTF1 / NKX2.1, Clone: 8G7G3/1, Novus Biologicals™

$321.00 - $429.00

Specifications

Clone 8G7G3/1
Host Species Mouse
Isotype IgG1
Immunogen A full length recombinant rat TTF-1 protein was used as the immunogen for the 8G7G3/1 antibody.
Antigen TTF1 / NKX2.1
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 Disclaimers

For Research Use Only

Products
Catalog Number Mfr. No. Conjugate Quantity Price Quantity    

NBP2294341M

 
novus biologicals canada
NBP2294341ML
Unlabeled 1mL Each for $429.00

NBP229434

 
novus biologicals canada
NBP229434
Unlabeled 0.5mL Each for $321.00
Description & Specifications

Specifications

Clone 8G7G3/1
Host Species Mouse
Isotype IgG1
Immunogen A full length recombinant rat TTF-1 protein was used as the immunogen for the 8G7G3/1 antibody.
Antigen TTF1 / NKX2.1
Monoclonal or Polyclonal Monoclonal
Format Concentrated
Primary or Secondary Primary
Regulatory Status RUO
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Test Specificity Recognizes a protein of 40kDa, identified as Thyroid transcription factor-1 (TTF-1). TTF-1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. Anti-TTF-1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates. Loss of TTF-1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. TTF-1 reactivity is also seen in thyroid malignancies.
Gene Accession No. P43699
Gene ID (Entrez) 7080
Formulation Culture Medium