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anti-SUMO1, Clone: SM1/495, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP232901

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 Disclaimers

For Research Use Only

Catalog No. NBP232901

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Description & Specifications

Specifications

Primary or Secondary Primary
Applications ELISA
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Monoclonal or Polyclonal Monoclonal
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Quantity 0.5mL
Host Species Mouse
Clone SM1/495
Regulatory Status RUO
Formulation PBS with 0.05% BSA.
Gene Accession No. P63165
Gene ID (Entrez) 7341
Concentration 0.2mg/mL
Conjugate Unlabeled
Test Specificity This MAb is specific to SUMO-1 and shows no cross-reaction with either SUMO-2 or SUMO-3. The small ubiquitin-related modifier (SUMO) proteins, which include SUMO-1, SUMO-2 and SUMO-3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2, and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO-1 protein localizes to the nuclear membrane. Shows broad species reactivity.
Isotype κ
Format Purified
Antigen SUMO1
Immunogen Recombinant human SUMO1 protein