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anti-p73, Clone: 5B429, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP2-24737

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 Disclaimers

For Research Use Only

Catalog No. NBP224737

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Description & Specifications

Specifications

Antigen p73
Applications Chromatin Immunoprecipitation
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Simple Western
Applications Western Blotting
Clone 5B429
Concentration 0.5mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Mouse
Format Purified
Formulation 100μg in 200μL PBS containing 0.05% BSA
Gene Accession No. O15350
Host Species Mouse
Immunogen This antibody was raised against full-length human p73. It reacts with an epitope that is located on the N-terminal region of human p73. It does not cross react with p53.
Isotype κ
Quantity 0.1mg
Regulatory Status RUO
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Gene ID (Entrez) 7161
Test Specificity p73 antibody (clone 5B429) recognizes all of the TAp73 isoforms i.e. isoforms with an intact NH2-terminal transactivation domain (Thottassery et el, 2006, PMID 16505115). Sayan et al 2005 (PMID 15781249) showed that p73 IMG-246/ NBP2-24737 reacted with all tested TAp73 isoforms but not deltaNp73 whereas p73 antibody clone 5B1288 (NB100-56674/IMG-259A ) showed reactivity against all p73 isoforms including delta Np73. Caspase-cleaved p73 fragments, including 55 kDa and 45 kDa, have been described in literature (Sayan et al, 2008). p73 antibody clone 5B429 has also been referred to as 429 in the literature. This antibody is reactive to Human and Mouse.