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anti-MUC-1, Clone: E29, Novus Biologicals™

$321.00 - $429.00

Specifications

Clone E29
Host Species Mouse
Isotype λ
Immunogen A delipidated extract of human milk fat globule membranes was used as the immunogen for the MUC-1 (EMA) E29 antibody.
Antigen MUC-1
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 Disclaimers

For Research Use Only

Products
Catalog Number Mfr. No. Conjugate Quantity Price Quantity    

NBP229401

 
novus biologicals canada
NBP229401
Unlabeled 0.5mL Each for $321.00

NBP2294011M

 
novus biologicals canada
NBP2294011ML
Unlabeled 1mL Each for $429.00
Description & Specifications

Specifications

Clone E29
Host Species Mouse
Isotype λ
Immunogen A delipidated extract of human milk fat globule membranes was used as the immunogen for the MUC-1 (EMA) E29 antibody.
Antigen MUC-1
Monoclonal or Polyclonal Monoclonal
Format Concentrated
Primary or Secondary Primary
Regulatory Status RUO
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Test Specificity In Western blotting, it recognizes proteins in MW range of 265-400kDa, identified as different glycoforms of EMA. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit and the C-terminal beta subunit. The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. EMA may provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain, which is involved in cell signaling, through phosphorylations and protein-protein interactions. In immunohistochemical assays, it superbly stains routine formalin/paraffin carcinoma tissues. Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.
Gene Accession No. P15941
Gene ID (Entrez) 4582
Formulation Culture Medium