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anti-Moesin, Clone: MSN491, Novus Biologicals™

Manufacturer: novus biologicals canada  NBP2-32875

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For Research Use Only

Catalog No. NBP232875


Description & Specifications


Antigen Moesin
Applications ELISA
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Clone MSN491
Concentration 0.2mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Format Purified
Formulation PBS with 0.05% BSA.
Gene Accession No. P26038
Host Species Mouse
Immunogen Recombinant human Moesin protein
Isotype κ
Quantity 0.5mL
Regulatory Status RUO
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Gene ID (Entrez) 4478
Test Specificity Recognizes 78kDa moesin protein. Moesin, a member of the talin-4.1 superfamily, is a linking protein of the sub-membranous actin cytoskeleton. It is expressed in variable amounts in cells of different phenotypes such as macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. The ERM proteins, ezrin, radixin, and moesin are involved in a variety of cellular functions, such as cell adhesion, migration, and the organization of cell surface structures, and are highly homologous, both in protein sequence and in functional activity, with merlin/schwannomin, a neurofibromatosis-2-associated tumor-suppressor protein. Cell lines of epithelial and mesothelial origin contain both moesin and radixin whereas cells of endothelial and lymphoid origin express moesin.