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anti-Cytokeratin, HMW, Clone: 34bE12, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP2294171ML

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 Disclaimers

For Research Use Only

Catalog No. NBP2294171M

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Description & Specifications

Specifications

Isotype IgG1
Format Concentrated
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Quantity 1mL
Clone 34bE12
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Immunogen Solublized keratin extract from human stratum corneum was used as the immunogen for the Cytokeratin 34bE12 antibody.
Antigen Cytokeratin
Test Specificity This antibody recognizes CK1, CK5, CK10 and CK14. In normal epithelia, it stains stratified epithelia, myoepithelial cells and basal cells in the prostate gland and bronchi. This MAb shows no reactivity with hepatocytes, pancreatic acinar cells, proximal renal tubules, or endometrial glands; there is no reactivity with cells derived from simple epithelia. Mesenchymal tumors, lymphomas, melanomas, neural tumors, and neuroendocrine tumors are negative with this antibody. It stains myoepithelial cells and has been shown to be useful in distinguishing prostate adenocarcinoma from benign prostate. This antibody has also been useful in separating benign from malignant intraductal breast proliferations.
Formulation Culture Medium
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Gene Accession No. P13646
Regulatory Status RUO
Gene ID (Entrez) 51350
Conjugate Unlabeled
Host Species Mouse