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anti-cleaved Retinoblastoma 1, Clone: 172C1094, Novus Biologicals™

$139.00 - $309.05

Specifications

Clone 172C1094
Host Species Murine
Isotype IgG1
Immunogen A synthetic peptide corresponding to a region of the caspase-3-induced cleavage site of human Rb was used as immunogen.
Antigen cleaved Retinoblastoma 1
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Disclaimers:

For Research Use Only



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Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
NB10056598T Novus Biologicals Canada
NB10056598SS
0.025mg Each for $139.00
NB10056598 Novus Biologicals Canada
NB10056598
0.1mg Each for $309.05
Specifications Description & Specifications

Specifications

172C1094
IgG1
cleaved Retinoblastoma 1
Purified
RUO
The antibody recognizes cleaved Rb (DRb-p70). The antibody does not recognize full-length Rb. In camptothecin treated HL60, an ∽68 kDa band is observed. DRb-p70 exists in vivo as an N-terminally truncated form of Rb (Liu et al.). DRb-p70 is thought to be the product of alternative translation and is expressed in primary myeloid cells in fetal liver, bone marrow and spleen. DRb-p70 is also specifically expressed in tumor-associated macrophages (TAMs). TAMs are an important targets of cancer therapy. DRb-p70 is a marker of TAMs, and maybe useful for identifying tumors with macrophage infiltration (Liu et al, 2005).
PBS containing 0.05% BSA
Murine
A synthetic peptide corresponding to a region of the caspase-3-induced cleavage site of human Rb was used as immunogen.
Monoclonal
Primary
Immunohistochemistry,Immunohistochemistry (Frozen),Immunohistochemistry (Paraffin),Western Blot
5925
0.5mg/mL