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anti-CD63, Clone: NKI/C3, Novus Biologicals™

$321.00 - $429.00

Specifications

Clone NKI/C3
Host Species Mouse
Isotype κ
Immunogen Smooth plasma membrane fraction of MeWo cells
Antigen CD63
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 Disclaimers

For Research Use Only

Products
Catalog Number Mfr. No. Conjugate Quantity Price Quantity    

NBP2328291M

 
novus biologicals canada
NBP2328291ML
Unlabeled 1mL Each for $429.00

NBP232829

 
novus biologicals canada
NBP232829
Unlabeled 0.5mL Each for $321.00
Description & Specifications

Specifications

Clone NKI/C3
Host Species Mouse
Isotype κ
Immunogen Smooth plasma membrane fraction of MeWo cells
Antigen CD63
Monoclonal or Polyclonal Monoclonal
Format Purified
Primary or Secondary Primary
Regulatory Status RUO
Applications ELISA
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Test Specificity This MAb recognizes protein of 26kDa-60kDa, which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.
Gene Accession No. P08962
Gene ID (Entrez) 967
Formulation PBS with 0.05% BSA.
Concentration 0.2mg/mL