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anti-CD45RB, Clone: PD7/26, Novus Biologicals™

$321.00 - $429.00

Specifications

Clone PD7/26
Host Species Mouse
Isotype κ
Immunogen Human peripheral blood lymphocytes maintained in T-cell growth factor was used as the immunogen for the CD45RB PD7/26 antibody.
Antigen CD45RB
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 Disclaimers

For Research Use Only

Products
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NBP2296321M

 
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NBP2296321ML
Unlabeled 1mL Each for $429.00

NBP229632

 
novus biologicals canada
NBP229632
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Description & Specifications

Specifications

Clone PD7/26
Host Species Mouse
Isotype κ
Immunogen Human peripheral blood lymphocytes maintained in T-cell growth factor was used as the immunogen for the CD45RB PD7/26 antibody.
Antigen CD45RB
Monoclonal or Polyclonal Monoclonal
Format Concentrated
Primary or Secondary Primary
Regulatory Status RUO
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Test Specificity CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45R functions as a phosphor-tyrosine phosphatase. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.
Gene Accession No. P08575
Gene ID (Entrez) 5788
Formulation Culture Medium