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LIMK1, Mouse, Clone: 4F9, Abnova™
Mouse monoclonal antibody raised against a partial recombinant LIMK1.
Supplier: Abnova Corporation H00003984M04
Description
There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is likely to be a component of an intracellular signaling pathway and may be involved in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome. [provided by RefSeq
Sequence: ADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKLEHWLETLRMHLAGHLPLGPQLEQLDRGFWETYRRGESGLPAHPEVPDSpecifications
| LIMK1 | |
| Monoclonal | |
| Unconjugated | |
| PBS with no preservative; pH 7.4 | |
| NM_002314 | |
| LIMK1 | |
| LIMK1 (NP_002305, 548 a.a. ∼ 647 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG2a κ |
| ELISA, Western Blot | |
| 4F9 | |
| Mouse monoclonal antibody raised against a partial recombinant LIMK1. | |
| LIMK1 | |
| LIMK | |
| Mouse | |
| Affinity chromatography | |
| RUO | |
| 3984 | |
| Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | |
| Liquid |