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IRP2 Polyclonal Antibody, Invitrogen™


IRP2 Antibody, PA1-16544, from Invitrogen™. Species Reactivity: Mouse; Applications: Gel Shift, ICC, IF, IHC, IHC (Paraffin), WB.

Manufacturer: pierce biotechnology inc  PA116544

Catalog No. APPA6544

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Description & Specifications

Specifications

Formulation 100μL purified antibody (1.15mg/mL) in tris glycine with 0.15M NaCl and 0.05% sodium azide
Gene Symbols IREB2
Gene ID (Entrez) 64602
Applications Gel Shift
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry
Applications Immunohistochemistry (Paraffin)
Applications Western Blot
Storage Requirements avoiding freeze/thaw cycles.
Gene Alias Iron-responsive element binding protein 2, IRE-BP 2, Iron regulatory protein 2
Isotype IgG
Species Reactivity Mouse
Gene Accession No. Q811J3
Antigen IRP2
Cross Reactivity Mouse
Host Species Rabbit
Primary or Secondary Primary
Conjugate Unlabeled
Monoclonal or Polyclonal Polyclonal
Format Purified
Immunogen A synthetic peptide made to an internal portion of the murine IRP2 protein sequence (between residues 100-200). UniProt Q811J3
Quantity 100μL

IRP2 Antibody, PA1-16544, from Invitrogen. Species Reactivity: Mouse; Applications: Gel Shift, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot.

Iron regulatory protein 2 (IRP2) is a central post-transcriptional regulator of cellular and systemic iron metabolism. It is a cytosolic RNA-binding protein that binds to stem-loop structures. IRP2 is regulated by iron-mediated proteolysis. Hypoxia is important for normal tissue physiology as well as being a component of several pathophysiological conditions, including heart and cerebrovascular diseases and tumor growth. Because iron and oxygen are closely related, IRP2 also plays a role during hypoxia (low oxygen).
Host Species: Rabbit
Cross Reactivity: Mouse
Isotype: IgG
Immunogen: A synthetic peptide made to an internal portion of the murine IRP2 protein sequence (between residues 100-200). UniProt Q811J3
Formulation: 100μL purified antibody (1.15mg/mL) in tris glycine with 0.15M NaCl and 0.05% sodium azide
Synonyms: Iron-responsive element binding protein 2, IRE-BP 2, Iron regulatory protein 2
Uniprot Accession: Q811J3
Entrez GeneID: 64602
Gene Symbol: IREB2
This antibody has 94% sequence homology with human, primate and rat. Suggested positive control: 3T3 whole cell lysate.