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IRP2 Polyclonal Antibody, Invitrogen™


IRP2 Antibody, PA1-16544, from Invitrogen™. Species Reactivity: Mouse; Applications: Gel Shift, ICC, IF, IHC, IHC (Paraffin), WB.

Manufacturer: pierce biotechnology inc  PA116544

Catalog No. APPA6544

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Description & Specifications

Specifications

Antigen IRP2
Applications Gel Shift
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry
Applications Immunohistochemistry (Paraffin)
Applications Western Blot
Conjugate Unlabeled
Cross Reactivity Mouse
Format Purified
Formulation 100μL purified antibody (1.15mg/mL) in tris glycine with 0.15M NaCl and 0.05% sodium azide
Gene Accession No. Q811J3
Gene Alias Iron-responsive element binding protein 2, IRE-BP 2, Iron regulatory protein 2
Gene Symbols IREB2
Host Species Rabbit
Immunogen A synthetic peptide made to an internal portion of the murine IRP2 protein sequence (between residues 100-200). UniProt Q811J3
Isotype IgG
Quantity 100μL
Species Reactivity Mouse
Storage Requirements avoiding freeze/thaw cycles.
Primary or Secondary Primary
Monoclonal or Polyclonal Polyclonal
Gene ID (Entrez) 64602

IRP2 Antibody, PA1-16544, from Invitrogen. Species Reactivity: Mouse; Applications: Gel Shift, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot.

Iron regulatory protein 2 (IRP2) is a central post-transcriptional regulator of cellular and systemic iron metabolism. It is a cytosolic RNA-binding protein that binds to stem-loop structures. IRP2 is regulated by iron-mediated proteolysis. Hypoxia is important for normal tissue physiology as well as being a component of several pathophysiological conditions, including heart and cerebrovascular diseases and tumor growth. Because iron and oxygen are closely related, IRP2 also plays a role during hypoxia (low oxygen).
Host Species: Rabbit
Cross Reactivity: Mouse
Isotype: IgG
Immunogen: A synthetic peptide made to an internal portion of the murine IRP2 protein sequence (between residues 100-200). UniProt Q811J3
Formulation: 100μL purified antibody (1.15mg/mL) in tris glycine with 0.15M NaCl and 0.05% sodium azide
Synonyms: Iron-responsive element binding protein 2, IRE-BP 2, Iron regulatory protein 2
Uniprot Accession: Q811J3
Entrez GeneID: 64602
Gene Symbol: IREB2
This antibody has 94% sequence homology with human, primate and rat. Suggested positive control: 3T3 whole cell lysate.