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Histone H3 Polyclonal Antibody, Invitrogen™


Histone H3 Antibody, PA1-16941, from Invitrogen™. Species Reactivity: Human, Mouse; Applications: Western Blot.

Manufacturer: pierce biotechnology inc  PA116941

Catalog No. 01-950-250

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Description & Specifications

Specifications

Applications Western Blot
Formulation 100μL purified antibody (18mg/mL) in PBS and 0.02% sodium azide
Cross Reactivity Human
Cross Reactivity Mouse
Gene Symbols HIST1H3A
Storage Requirements Avoid Freeze/Thaw Cycles
Gene Alias Histone H3, Histone 1, H3a, Histone H3.1, histone H3/a, HIST1H3A
Species Reactivity Human, Mouse
Gene ID (Entrez) 360198, 8350
Isotype IgG
Gene Accession No. P68431, P68433
Format Purified
Immunogen Synthetic peptide between amino acids 100-135 of the human Histone H3 protein.
Quantity 100μL
Conjugate Unlabeled
Primary or Secondary Primary
Monoclonal or Polyclonal Polyclonal
Host Species Rabbit
Antigen Histone H3

Histone H3 Antibody, PA1-16941, from Invitrogen. Species Reactivity: Human, Mouse; Applications: Western Blot.

In diploid eukaryotic cells, the chromatin fibers are about 20nM in diameter. They consist of two major components in equal amounts, DNA and basic proteins called histones. Histones are believed to be regularly arranged in the deep grove of the DNA helix. The recurring positive charges of the histones form electrostatic associations with the negatively charged phosphate groups of DNA making the DNA more stable and flexible. This allows for the supercoiling of the chromatin fibers.
Host Species: Rabbit
Cross Reactivity: Human, Mouse
Isotype: IgG
Immunogen: Synthetic peptide between amino acids 100-135 of the human Histone H3 protein.
Formulation: 100μL purified antibody (18mg/mL) in PBS and 0.02% sodium azide
Synonyms: Histone H3, Histone 1, H3a, Histone H3.1, histone H3/a, HIST1H3A
Uniprot Accession: P68431, P68433
Entrez GeneID: 360198, 8350
Gene Symbol: HIST1H3A
This antibody is expected to cross react with all mammals and a wide range of other species based on sequence homology. Suggested positive control: Hela whole cell lysate, MEF and HeLa lysates, MEF whole cell lysate0.