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GDNF Sheep anti-Human, Mouse, Rat, Polyclonal, Invitrogen

Sheep Polyclonal Antibody

Manufacturer:  Invitrogen PA118367

Catalog No. 01-670-619



Description

Description

PA1-18367 detects GDNF from human, mouse, and rat samples. PA1-18367 has been successfully used in Western blot procedures. The PA1-18367 immunogen is recombit human GDNF. Reconstitute with 100 μL of distilled water.

GDNF is a glycosylated, disulfide-bonded homodimer molecule. It was first discovered as a potent survival factor for midbrain dopaminergic neurons and was then shown to rescue these neurons in animal models of Parkinson′s disease. GDNF is about 100 times more efficient survival factor for spinal motor neurons than the neurotrophins. GDNF is a neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
Specifications

Specifications

GDNF
Polyclonal
whole serum with no preservative
P48540, P39905, Q07731
Glial cell line-derived neurotrophic factor, Astrocyte-derived trophic factor 1, ATF1, ATF2, HFB1-GDNF
Sheep
IgG
RUO
Antibody
Polyclonal
Human,Mouse,Rat
Western Blot
Unconjugated
GDNF
Lyophilized
GDNF
Recombit human GDNF.
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
25453, 2668, 14573
SDS
Documents