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GDNF Polyclonal Antibody, Invitrogen™

Sheep Polyclonal Antibody

Supplier:  Invitrogen PA118367

Catalog No. 01-670-619


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Description

Description

Reconstitute in 100 μL of sterile water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20 °C for a higher stability, and at 4 °C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.

GDNF is a glycosylated, disulfide-bonded homodimer molecule. It was first discovered as a potent survival factor for midbrain dopaminergic neurons and was then shown to rescue these neurons in animal models of Parkinson's disease. GDNF is about 100 times more efficient survival factor for spinal motor neurons than the neurotrophins. GDNF is a neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
Specifications

Specifications

GDNF
Polyclonal
Unconjugated
GDNF
AI385739; Astrocyte-derived trophic factor; ATF; ATF1; ATF2; Gdnf; glial cell derived neurotrophic factor; glial cell line derived neurotrophic factor; Glial cell line derived neutrophic factor; glial cell line-derived neurotrophic factor; gndf; HFB1-GDNF; hGDNF; H-GDNF; HSCR3; mGDNF; neurotrophic factor
Sheep
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
Western Blot
Conc. Not Determined
whole serum with no preservative
P39905, P48540, Q07731
GDNF
Recombinant human GDNF.
RUO
14573, 25453, 2668
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
SDS
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