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X-ray repair complementing defective repair in Chinese hamster cells 6, Mouse, Clone: 4C2-1A6, Abnova™
Mouse monoclonal antibody raised against a full-length recombinant XRCC6.
Supplier: Abnova Corporation H00002547M01
Description
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq
Sequence: MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPFDMSIQCIQSVYISKIISSDRDLLAVVFYGTEKDKNSVNFKNIYVLQELDNPGAKRILELDQFKGQQGQKRFQDMMGHGSDYSLSEVLWVCANLFSDVQFKMSHKRIMLFTNEDNPHGNDSAKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISLFYRDIISIAEDEDLRVHFEESSKLEDLLRKVRAKETRKRALSRLKLKLNKDIVISVGIYNLVQKALKPPPIKLYRETNEPVKTKTRTFNTSTGGLLLPSDTKRSQIYGSRQIILEKEETEELKRFDDPGLMLMGFKPLVLLKKHHYLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVAALCRYTPRRNIPPYFVALVPQEEELDDQKIQVTPPGFQLVFLPFADDKRKMPFTEKIMATPEQVGKMKAIVEKLRFTYRSDSFENPVLQQHFRNLEALALDLMEPEQAVDLTLPKVEAMNKRLGSLVDEFKELVYPPDYNPEGKVTKRKHDNEGSGSKRPKVEYSEEELKTHISKGTLGKFTVPMLKEACRAYGLKSGLKKQELLEALTKHFQDSpecifications
| X-ray repair complementing defective repair in Chinese hamster cells 6 | |
| Monoclonal | |
| Unconjugated | |
| PBS with no preservative; pH 7.4 | |
| BC008343 | |
| XRCC6 | |
| XRCC6 (AAH08343.1, 1 a.a. ∼ 609 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody |
| ELISA, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot | |
| 4C2-1A6 | |
| Mouse monoclonal antibody raised against a full length recombinant XRCC6. | |
| XRCC6 | |
| CTC75/CTCBF/G22P1/KU70/ML8/TLAA | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| 2547 | |
| Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | |
| IgG1 κ |