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Endothelin Receptor A Polyclonal Antibody, Invitrogen™


Endothelin Receptor A Antibody, PA3-065, from Invitrogen™. Species Reactivity: Human, Mouse, Rat; Applications: ICC, IF, IHC (Frozen), IHC (Paraffin), WB.

Manufacturer: pierce biotechnology inc  PA3065

Catalog No. PIPA3065

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Description & Specifications

Specifications

Antigen Endothelin Receptor A
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Western Blot
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Format Serum
Formulation 100μL unpurified antibody in whole serum and 0.02% sodium azide
Gene Accession No. P25101, P26684, Q61614
Gene Alias ET-A, G-protein coupled receptor 10, endothelin A receptor, endothelin-1 receptor
Gene Symbols EDNRA
Host Species Rabbit
Immunogen COOH-terminal amino acids of mouse ETA (408-427) KNQEQNNHNTERSSHKDSMN coupled to KLH
Isotype IgG
Quantity 100μL
Species Reactivity Human, Mouse, Rat
Storage Requirements Avoid Freeze/Thaw Cycles
Primary or Secondary Primary
Monoclonal or Polyclonal Polyclonal
Gene ID (Entrez) 13617, 1909, 24326

Endothelin Receptor A Antibody, PA3-065, from Invitrogen. Species Reactivity: Human, Mouse, Rat; Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot.

This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants.
Host Species: Rabbit
Cross Reactivity: Human, Mouse, Rat
Isotype: IgG
Immunogen: COOH-terminal amino acids of mouse ETA (408-427) KNQEQNNHNTERSSHKDSMN coupled to KLH
Formulation: 100μL unpurified antibody in whole serum and 0.02% sodium azide
Synonyms: ET-A, G-protein coupled receptor 10, endothelin A receptor, endothelin-1 receptor
Uniprot Accession: P25101, P26684, Q61614
Entrez GeneID: 13617, 1909, 24326
Gene Symbol: EDNRA
PA3-065 detects Endothelin Receptor A from human, mouse, and rat samples. PA3-065 has been successfully used in Western blot, immunocytochemistry, and immunohistochemistry procedures. By western blot, this antibody detects a 46kDa protein corresponding to mouse Endothelin Receptor A.
References:
Test: IHC (P), Species: Hu, Reference: Reassessment of endothelin receptor A expression in normal and neoplastic human tissues using the novel rabbit monoclonal antibody UMB-8. (Apr 2015) Peptides, Vol: 66, , 19-25, Lupp A,Mann A,Heeb A,Kaemmerer D,Sänger J,Evert M,Evert K,Mawrin C,Schulz S; Pubmed ID: 25708416