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anti-ELK Rec. Tyrosine Kinase Polyclonal, Thermo Scientific™


ELK Rec. Tyrosine Kinase Polyclonal Ab PA1-12409 from Thermo Scientific™ specifically detects ELK Rec. Tyrosine Kinase in Hu samples, and it is validated for IP

Manufacturer: pierce biotechnology inc  PA112410

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Catalog No. 01-674-139

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Description & Specifications

Specifications

Antigen ELK Rec. Tyrosine Kinase
Applications Immunoprecipitation
Conjugate Unlabeled
Cross Reactivity Human
Format Purified
Formulation 250μg purified antibody in PBS and 0.08% sodium azide
Gene Accession No. P54762
Gene Alias ELK, EPHT2, FLJ37986, Hek6, NET
Gene Symbols EPHB1
Host Species Sheep
Immunogen Recombinant protein corresponding to residues 883-984 of C terminus of human ephB1.
Isotype IgG
Quantity 250μg
Species Reactivity Human
Storage Requirements Avoid Freeze/Thaw Cycles
Primary or Secondary Primary
Monoclonal or Polyclonal Polyclonal
Gene ID (Entrez) 2047

ELK Rec. Tyrosine Kinase Polyclonal Ab PA1-12409 from Thermo Scientific™ specifically detects ELK Rec. Tyrosine Kinase in Hu samples, and it is validated for IP

ephB1, previously known as Elk(eph-like kinase), is a receptor tyrosine kinase of the highly tissue restricted family of eph proteins. EphB1 and other ephB family members are type 1 membrane spanning proteins, comprised of immunoglobulin, fibronectin type III, and cysteine rich subdomains in the ecto domain, and the single uninterrupted cytoplasmic tyrosine kinase domain upstream of a carboxyterminal sterile alpha motif (SAM) domain. ephB family proteins bind ephrins of the B class, ligands that are also transmembrane spanning proteins capable of transmitting signals. ephB1 is expressed predominantly in developing neural structures in embryos, and in vascular epithelium of kidney, and other tissues. Upon binding to alternatively oligomerized ephrin B1, ephB1 signals regulation of cell attachment and cellcell assembly. Members of this protein family are implicated in neuronal and vascular cell targeting.
Host Species: Sheep
Cross Reactivity: Human
Isotype: IgG
Immunogen: Recombinant protein corresponding to residues 883-984 of C terminus of human ephB1.
Formulation: 250μg purified antibody in PBS and 0.08% sodium azide
Synonyms: ELK, EPHT2, FLJ37986, Hek6, NET
Uniprot Accession: P54762
Entrez GeneID: 2047
Gene Symbol: EPHB1
A suggested positive control for this product is human brain lysate.