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CENPF Polyclonal Antibody, Invitrogen™


CENPF Antibody, PA1-16826, from Invitrogen™. Species Reactivity: Bovine, Human; Applications: FACS, ICC, IF, IP, WB.

Manufacturer: pierce biotechnology inc  PA116826

Catalog No. APPA6826

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Description & Specifications

Specifications

Antigen CENPF
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunoprecipitation
Applications Western Blot
Conjugate Unlabeled
Cross Reactivity Bovine
Cross Reactivity Human
Format Purified
Formulation 50μL purified antibody (2.5mg/mL) in PBS with 50% glycerol and 0.05% sodium azide
Gene Accession No. P49454
Gene Alias AH Antigen, CENF, CENP F Kinetochore Protein, Centromere Protein F, Mitosin, CENPF
Gene Symbols CENPF
Host Species Rabbit
Immunogen A bacterial fusion protein from the C-terminus of CENP-F.
Isotype IgG
Quantity 50μL
Species Reactivity Bovine, Human
Storage Requirements Avoid Freeze/Thaw Cycles
Primary or Secondary Primary
Monoclonal or Polyclonal Polyclonal
Gene ID (Entrez) 1063
Target Species Bovine
Target Species Human

CENPF Antibody, PA1-16826, from Invitrogen. Species Reactivity: Bovine, Human; Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot.

The kinetophore is a macromolecular structure that is associated with the centromeres of chromosomes and is responsible for establishing and maintaining the connections with the microtubules of the mitotic spindle. The proteins that reside within the chromosomal domain fall into two broad classes: those that associate with the centromere throughout the cell cycle and those that are found at the centromere in a cell cycle specific manner. Members of the first class include CENP-A, CENP-B, and CENP-C. The members of the second class include several ubiquitous cellular proteins such as calmodulin, tubulin, dynein and p34 cdc2 and also CENP-E and CENP-F. CENP-F appears to be the earliest member to interact with the centromere-kinetochore complex. CENP-F also shows a cell-cycle distribution that is both temporally regulated and diverse in terms of the structural components it localizes to and therefore may play a role in several mitotic events.
Host Species: Rabbit
Cross Reactivity: Bovine, Human
Isotype: IgG
Immunogen: A bacterial fusion protein from the C-terminus of CENP-F.
Formulation: 50μL purified antibody (2.5mg/mL) in PBS with 50% glycerol and 0.05% sodium azide
Synonyms: AH Antigen, CENF, CENP F Kinetochore Protein, Centromere Protein F, Mitosin, CENPF
Uniprot Accession: P49454
Entrez GeneID: 1063
Gene Symbol: CENPF
Suggested positive control: HeLa and SK-N-SH cells.