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MilliporeSigma™ anti-CD45, PE-Cy7, Clone: 30-F11,
Rat Monoclonal Antibody
Supplier: MilliporeSigma™ MABF1464
Description
Specifically detects CD45 Clone: 30-F11 in Mouse samples, and it is validated for Flow Cytometry
The 30-F11 antibody reacts with mouse CD45, which is one of the most abundant hematopoietic markers and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, CD45RO and others. The 30-F11 antibody is widely used as a leukocyte marker for B cells, T cell subsets and NK cell subsets.Specifications
| CD45 | |
| Monoclonal | |
| PE-Cyanine7 | |
| P06800 | |
| Rat | |
| Purified by size-exclusion chromatography | |
| RUO | |
| Primary | |
| 2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze | |
| IgG2b κ |
| Flow Cytometry | |
| 30-F11 | |
| Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1%Â gelatin, pH 7.2. | |
| Ptprc, Ly-5 | |
| Proprietary immunogen | |
| 25 μg | |
| Inflammation, Immunology | |
| Mouse | |
| Purified |
For Research Use Only