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anti-CD44 Violer Fluor 450, Clone: IM7, EMD Millipore™

Rat Monoclonal Antibody

Manufacturer:  Millipore Sigma MABF1562

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Catalog No. MABF1562MI



Description

Description

Specifically detects CD44 Clone: IM7 in Human, Mouse samples, and it is validated for Flow Cytometry

The IM7 antibody recognizes CD44, a ubiquitously expressed cell surface receptor which is important for extracellular matrix organization, cell-cell and cell-matrix adhesion and migration. CD44 may be expressed in a number of different isoforms (splice variants) from the most typical or 'standard' form, known as CD44s, to variants designated CD44v, e.g. CD44v1 or CD44v6. These receptors interact with several ligands, but most often associate with an extracellular matrix component hyaluronate, through which it mediates adhesion.The IM7 antibody may be used for detection of all isoforms of CD44, as it recognizes constant epitopes near the extracellular proximal domain. (Xu et al, 2002, J. Leukoc. Biol. 72:1133-1141). It has been reported to be cross-reactive with many non-human species including Baboon, Chimpanzee, Cynomolgus, Rhesus, Horse, Cow, Pig, Dog and Cat CD44.
Specifications

Specifications

CD44
IM7
Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Purified
Rat
Purified by size-exclusion chromatography
RUO
2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Monoclonal
Flow Cytometry
Violet Fluor 450
P15379
Cd44, Ly-24
Proprietary immunogen
100μg
Inflammation, Immunology
Primary
Human, Murine
Documents

For Research Use Only