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CBL (M01), Mouse anti-Human, Clone: 6D12, Abnova™
Mouse monoclonal antibody raised against a partial recombinant CBL.
Supplier: Abnova Corporation H00000867M01C
Description
The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. [provided by RefSeq
Sequence: NIQSQAPSITESSTFGEGNLAAAHANTGPEESENEDDGYDVPKPPVPAVLARRTLSDISNASSSFGWLSLDGDPTTNVTEGSQVPERPPKPFPRRINSERSpecifications
| CBL | |
| Monoclonal | |
| Unconjugated | |
| tissue culture supernatant with no preservative | |
| NM_005188 | |
| CBL | |
| CBL (NP_005179, 736 a.a. ∼ 835 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| RUO | |
| 867 | |
| Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | |
| Liquid |
| ELISA, Western Blot | |
| 6D12 | |
| Mouse monoclonal antibody raised against a partial recombinant CBL. | |
| CBL | |
| C-CBL/CBL2/RNF55 | |
| Mouse | |
| 200 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 κ |