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Caspase 10 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA112507

Catalog No. 01-674-167



Description

Description

A suggested positive control for this product is HeLa whole cell lysate.

Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.
Specifications

Specifications

Caspase 10
Polyclonal
PBS with 0.02% sodium azide
Q92851
CASP10
Synthetic peptide corresponding to residues 505-521 of human FLICE2.
100 μg
Primary
Human,Mouse,Rat
Antibody
IgG
Western Blot
Unconjugated
CASP10
ALPS2, FLICE2, MCH4
Rabbit
Antigen affinity chromatography
RUO
843
-20° C, Avoid Freeze/Thaw Cycles
Liquid
SDS
Documents
Product Certifications
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