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Caspase 10 Polyclonal Antibody, Invitrogen™


Caspase 10 Antibody, PA1-12507, from Invitrogen™. Species Reactivity: Human, Mouse, Rat; Applications: Western Blot.

Manufacturer: pierce biotechnology inc  PA112507

Catalog No. 01-674-167

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Description & Specifications

Specifications

Gene ID (Entrez) 843
Formulation 100μg purified antibody in PBS and 0.02% sodium azide
Applications Western Blotting
Gene Symbols CASP10
Gene Alias ALPS2, FLICE2, MCH4
Storage Requirements Avoid Freeze/Thaw Cycles
Gene Accession No. Q92851
Species Reactivity Human, Mouse, Rat
Isotype IgG
Antigen Caspase 10
Immunogen Synthetic peptide corresponding to residues 505-521 of human FLICE2.
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Primary or Secondary Primary
Conjugate Unlabeled
Monoclonal or Polyclonal Polyclonal
Host Species Rabbit
Quantity 100μg
Format Purified

Caspase 10 Antibody, PA1-12507, from Invitrogen. Species Reactivity: Human, Mouse, Rat; Applications: Western Blot.

Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.
Host Species: Rabbit
Cross Reactivity: Human, Mouse, Rat
Isotype: IgG
Immunogen: Synthetic peptide corresponding to residues 505-521 of human FLICE2.
Formulation: 100μg purified antibody in PBS and 0.02% sodium azide
Synonyms: ALPS2, FLICE2, MCH4
Uniprot Accession: Q92851
Entrez GeneID: 843
Gene Symbol: CASP10
A suggested positive control for this product is HeLa whole cell lysate.