c-Fos Sheep anti-Hamster, Rabbit, Rat, Polyclonal, Invitrogen™

Description

PA1-18329 detects c-FOS from rat, rabbit, and hamster samples. PA1-18329 has been successfully used in immunohistochemistry (paraffin and frozen) and Western blot procedures. The PA1-18329 immunogen is a synthetic peptide corresponding to the N-terminal residues M(2) F S G F N A D Y E A S S S R C(17), conjugated to diphtheria toxoid. The sequence is 100% conserved in human, rat, mouse, hamster, and cat. Reconstitute with 500 µL of distilled water.

c-FOS is a nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. It has a critical function in regulating the development of cells destined to form and maintain the skeleton, and is thought to have an important role in signal transduction, cell proliferation and differentiation.