Please login to your online account to display your discounted pricing

anti-BUB1B Polyclonal, Thermo Scientific™

BUB1B Polyclonal antibody PA1-12551 from Thermo Scientific™ specifically detects BUB1B in Mouse samples, and it is validated for Immunohistochemistry and Western Blot

$395.85 - $424.20

Specifications

Antigen BUB1B
Cross Reactivity Mouse
Format Purified
Host Species Sheep
Immunogen Recombinant protein corresponding to residues 883-1052 of mouse Bub1b.
View More Specs
Products
Catalog Number Mfr. No. Conjugate Quantity Price Quantity    

01-674-790

 
pierce biotechnology inc
PA112551
Unlabeled 250μg Each for $424.20

01-674-792

 
pierce biotechnology inc
PA112553
Unlabeled 250μg Each for $395.85

01-674-791

 
pierce biotechnology inc
PA112552
Unlabeled 250μg Each for $395.85
Description & Specifications

Specifications

Antigen BUB1B
Cross Reactivity Mouse
Format Purified
Host Species Sheep
Immunogen Recombinant protein corresponding to residues 883-1052 of mouse Bub1b.
Isotype IgG
Monoclonal or Polyclonal Polyclonal
Primary or Secondary Primary
Storage Requirements Avoid Freeze/Thaw Cycles

BUB1B Polyclonal antibody PA1-12551 from Thermo Scientific™ specifically detects BUB1B in Mouse samples, and it is validated for Immunohistochemistry and Western Blot

Compromised spindle checkpoints are thought to play an important role in genetic instability that predisposes cells to malignant transformations. Human cells contain two related checkpoint protein kinases, evolved from the BUB1 gene; hBUBR1 and hBUB1. They are important components of the spindle checkpoint Both kinases monitor mitotic kinetochore-microtubule interactions. hBUBR1 is essential for normal mitotic progression as it prevents cells from entering into anaphase too early. BUBR1 has been detected in human cancers. It has been identified as a novel binding partner of BCSG1 (Breast Cancer-Specific Gene 1), which has been suggested to accelerate the progression of breast cancer by compromising the mitotic checkpoint control through inactivation of BUBR1.
Host Species: Sheep
Cross Reactivity: Mouse
Isotype: IgG
Immunogen: Recombinant protein corresponding to residues 883-1052 of mouse Bub1b.
Formulation: 250μg purified Antibody (1mg/mL) in PBS, with 0.08% sodium azide;
Synonyms: BUB1beta, BUBR1, MAD3L, SSK1, hBUBR1
Uniprot Accession: Q9Z1S0
Gene Symbol: Bub1b
Entrez GeneID: 12236
PA1-12551 detects BUB1B in Mouse samples. PA1-12551 has been successfully used in Immunohistochemistry and Western Blot procedures. PA1-12551 The immunogen is Recombinant protein corresponding to residues 883-1052 of mouse Bub1b..