BNIP3L Polyclonal Antibody, Invitrogen™
BNIP3L Antibody, PA1-12514, from Invitrogen™. Species Reactivity: Human; Applications: Western Blot.
Manufacturer: Pierce Biotechnology Inc PA112514
BNIP3L Antibody, PA1-12514, from Invitrogen. Species Reactivity: Human; Applications: Western Blot.Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro apoptotic proteins, including Bad, Bax, Bid, Bik, Hrk, Nip3, and Bim, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bnip3L, Bnip3a, and Nix (for Nip3-like protein X Bnip3L/Bnip3a/Nix is a homolog of the E1B 19K/Bcl-2 binding and pro-apoptotic protein Bnip3. Overexpression of Bnip3L induces apoptosis. Bnip3L interacts with and overcomes suppresses by Bcl-2 and Bcl-xL. Bnip3L is localized in mitochondria.
Host Species: Rabbit
Cross Reactivity: Human
Immunogen: Synthetic peptide corresponding to residues 77-92 of human Bnip3L.
Formulation: 100μg purified antibody in PBS and 0.02% sodium azide
Synonyms: BNIP3a, NIX
Uniprot Accession: O60238
Entrez GeneID: 665
Gene Symbol: BNIP3L
A suggested positive control for this product is K562 cell lysate.
|Avoid Freeze/Thaw Cycles|
|100μg purified antibody in PBS and 0.02% sodium azide|
|Synthetic peptide corresponding to residues 77-92 of human Bnip3L.|
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