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BNIP3L Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Pierce Biotechnology Inc PA112514

Catalog No. 01-674-174



Description

Description

A suggested positive control for this product is K562 cell lysate.

Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro apoptotic proteins, including Bad, Bax, Bid, Bik, Hrk, Nip3, and Bim, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bnip3L, Bnip3a, and Nix (for Nip3-like protein X Bnip3L/Bnip3a/Nix is a homolog of the E1B 19K/Bcl-2 binding and pro-apoptotic protein Bnip3. Overexpression of Bnip3L induces apoptosis. Bnip3L interacts with and overcomes suppresses by Bcl-2 and Bcl-xL. Bnip3L is localized in mitochondria.
Specifications

Specifications

BNIP3L
Polyclonal
PBS with 0.02% sodium azide
O60238
BNIP3a, NIX
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
665
Western Blot
Unconjugated
BNIP3L
Liquid
BNIP3L
Synthetic peptide corresponding to residues 77-92 of human Bnip3L.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
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