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anti-Amyloid beta A4 Polyclonal, Thermo Scientific™


Amyloid beta A4 Polyclonal antibody PA1-18317 from Thermo Scientific™ specifically detects Amyloid beta A4 in Rat samples, and it is validated for Immunohistochemistry

Manufacturer: pierce biotechnology inc  PA118317

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Catalog No. 01-670-570

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Description & Specifications

Specifications

Antigen Amyloid beta A4
Applications Immunohistochemistry
Conjugate Unlabeled
Cross Reactivity Rat
Format Serum
Formulation 100μL unpurified antibody in whole serum and no preservative
Gene Accession No. P08592
Gene Alias APP, ABPP, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, CVAP; Protease nexin-II, PN-II, APPI, PreA4, A4, AD1
Gene Symbols APP
Host Species Rabbit
Immunogen C-H(388) A H F Q K A K E R L E A K H R E R(405)
Isotype IgG
Quantity 100μL
Species Reactivity Rat
Storage Requirements Avoid Freeze/Thaw Cycles
Primary or Secondary Primary
Monoclonal or Polyclonal Polyclonal
Gene ID (Entrez) 54226

Amyloid beta A4 Polyclonal antibody PA1-18317 from Thermo Scientific™ specifically detects Amyloid beta A4 in Rat samples, and it is validated for Immunohistochemistry

APP functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. The APP protein is involved in cell mobility and transcription regulation through protein-protein interactions. APP can promote transcription activation through binding to APBB1/Tip60 and inhibit Notch signaling through interaction with Numb. APP couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity. Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1.
Host Species: Rabbit
Cross Reactivity: Rat
Isotype: IgG
Immunogen: Synthetic peptides corresponding to residuess C-E(145) T H L H W H T V A K E T(157), C-H(388) A H F Q K A K E R L E A K H R E R(405), and C-K(724) K K
Formulation: 100μL unpurified antibody in whole serum and no preservative
Synonyms: APP, ABPP, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, CVAP; Protease nexin-II, PN-II, APPI, PreA4, A4, AD1
Uniprot Accession: P08592
Entrez GeneID: 54226
Gene Symbol: APP
PA1-18317 detects APP from rat samples. PA1-18317 has been successfully used in immunohistochemistry procedures. The PA1-18317 immunogen is a synthetic peptides corresponding to residuess C-E(145) T H L H W H T V A K E T(157), C-H(388) A H F Q K A K E R L E A K H R E R(405), and C-K(724) K K Q Y T S I H H G V V E(737) of human APP isoform A, conjugated to KLH. Reconstitute with 100 ul of distilled water.