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Amyloid beta A4 Polyclonal Antibody, Invitrogen™


Amyloid beta A4 Antibody, PA1-18317, from Invitrogen™. Species Reactivity: Rat; Applications: Immunohistochemistry.

Manufacturer: pierce biotechnology inc  PA118317

Catalog No. 01-670-570

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Description & Specifications

Specifications

Gene Symbols APP
Gene ID (Entrez) 54226
Formulation 100μL unpurified antibody in whole serum and no preservative
Immunogen C-H(388) A H F Q K A K E R L E A K H R E R(405)
Applications Immunohistochemistry
Gene Alias APP, ABPP, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, CVAP; Protease nexin-II, PN-II, APPI, PreA4, A4, AD1
Gene Accession No. P08592
Storage Requirements Avoid Freeze/Thaw Cycles
Isotype IgG
Species Reactivity Rat
Format Serum
Cross Reactivity Rat
Quantity 100μL
Antigen Amyloid beta A4
Conjugate Unlabeled
Primary or Secondary Primary
Monoclonal or Polyclonal Polyclonal
Host Species Rabbit

Amyloid beta A4 Antibody, PA1-18317, from Invitrogen. Species Reactivity: Rat; Applications: Immunohistochemistry.

APP functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. The APP protein is involved in cell mobility and transcription regulation through protein-protein interactions. APP can promote transcription activation through binding to APBB1/Tip60 and inhibit Notch signaling through interaction with Numb. APP couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity. Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1.
Host Species: Rabbit
Cross Reactivity: Rat
Isotype: IgG
Immunogen: Synthetic peptides corresponding to residuess C-E(145) T H L H W H T V A K E T(157), C-H(388) A H F Q K A K E R L E A K H R E R(405), and C-K(724) K K
Formulation: 100μL unpurified antibody in whole serum and no preservative
Synonyms: APP, ABPP, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, CVAP; Protease nexin-II, PN-II, APPI, PreA4, A4, AD1
Uniprot Accession: P08592
Entrez GeneID: 54226
Gene Symbol: APP
PA1-18317 detects APP from rat samples. PA1-18317 has been successfully used in immunohistochemistry procedures. The PA1-18317 immunogen is a synthetic peptides corresponding to residuess C-E(145) T H L H W H T V A K E T(157), C-H(388) A H F Q K A K E R L E A K H R E R(405), and C-K(724) K K Q Y T S I H H G V V E(737) of human APP isoform A, conjugated to KLH. Reconstitute with 100 ul of distilled water.