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ADFP Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Invitrogen PA116971

Catalog No. 01-670-217



Description

Description

This antibody is predicted to react with rat based on 84% sequence homology.

Milk lipid globules from humans, cows and rats contain a protein identified as adipocyte differentiation-related protein (ADFP). It is associated with the globule surface membrane material. This protein, previously believed to be specific to adipocytes, is a major constituent of the globule surface and is present in a detergent-insoluble complex that contains butyrophilin and xanthine oxidase. ADFP (Adipophilin) is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells. In tissues, however, expression of adipophilin is restricted to specific cell types, such as lactating mammary epithelial cells, adrenal cortex cells, Sertoli and Leydig cells of the male reproductive system, and steatosis or fatty change hepatocytes in alcoholic liver cirrhosis. ADFP may be a possible new marker for the identification of specialized differentiated cells containing lipid droplets and for diseases associated with fat-accumulating cells.
Specifications

Specifications

ADFP
Polyclonal
Unconjugated
PLIN2
Adipophilin antibody, adipose differentiation-related protein antibody, ADRP antibody
Rabbit
Antigen affinity chromatography
RUO
11520, 123
-20° C, Avoid Freeze/Thaw Cycles
Liquid
Immunohistochemistry (Paraffin), Western Blot
1.23 mg/mL
PBS with 30% glycerol and 0.05% sodium azide
Q99541, P43883
PLIN2
Synthetic peptide corresponding to the internal region (within residues 150-250) of human ADFP.
100 μL
Primary
Human, Mouse
Antibody
IgG
SDS
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