Please login to your online account to display your discounted pricing

anti-Acinus Polyclonal, Thermo Scientific™

Acinus Polyclonal antibody PA1-12497 from Thermo Scientific™ specifically detects Acinus in Human samples, and it is validated for Western Blot

Manufacturer: pierce biotechnology inc  PA112497

 View all options for this product

Catalog No. 01-674-157

 

Description & Specifications

Specifications

Antigen Acinus
Applications Western Blotting
Conjugate Unlabeled
Cross Reactivity Human
Format Purified
Formulation 100μg purified Antibody (0.5mg/mL) in PBS, with 0.02% sodium azide;
Gene Accession No. Q9UKV3
Gene Alias Apoptotic chromatin condensation inducer in the nucleus
Gene Symbols ACIN1
Host Species Rabbit
Immunogen 602-614 of human AcinusS' or 571-583 of human AcinusS
Isotype IgG
Quantity 100μg
Species Reactivity Human
Storage Requirements Avoid Freeze/Thaw Cycles
Primary or Secondary Primary
Monoclonal or Polyclonal Polyclonal
Gene ID (Entrez) 22985

Acinus Polyclonal antibody PA1-12497 from Thermo Scientific™ specifically detects Acinus in Human samples, and it is validated for Western Blot

Chromatin condensation and nuclear fragmentation (CCNF)is the hallmark of apoptosis. CCNF is triggered by the activation of members of caspase family, caspase activated DNase (CAD/DFF40), and several novel proteins including AIF and CIDE. A new inducer of chromatin condensation was recently identified and designated Acinus (for apoptotic chromatin condensation inducer in the nucleus). Acinus is cleaved by caspase-3 and an additional unknown protease generating a small active peptide p17, which causes chromatin condensation in vitro when it is added to purified nuclei. Acinus also induces apoptotic chromatin condensation in cells. Acinus is ubiquitously expressed.
Host Species: Rabbit
Cross Reactivity: Human
Isotype: IgG
Immunogen: Synthetic peptide (SRSTPVRDRGGRR) corresponding to aa 1329-1341 of human AcinusL, 602-614 of human AcinusS' or 571-583 of human AcinusS
Formulation: 100μg Purified Antibody (0.5mg/ml) in PBS, with 0.02% sodium azide
Synonyms: Apoptotic chromatin condensation inducer in the nucleus
Uniprot Accession: Q9UKV3
Entrez GeneID: 22985
Gene Symbol: ACIN1
A suggested positive control for this product is K562 cell lysate.