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Alfa Aesar™ Amphotericin B, Streptomyces nodosus

$78.96 - $974.62

Chemical Identifiers

CAS 1397-89-3
Molecular Formula C47H73NO17
Molecular Weight (g/mol) 924.091
MDL Number MFCD00877763
InChI Key APKFDSVGJQXUKY-IYVSRKHGSA-N
PubChem CID 134129663
IUPAC Name (1S,3R,18S,19R,20R,21S,25R,27R,30R,31R,33S,35R,37S,38R)-3-[(2R,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-19,25,27,30,31,33,35,37-octahydroxy-18,20,21-trimethyl-23-oxo-22,39-dioxabicyclo[33.3.1]nonatriaconta-4,6,8,10,12,14,16-heptaene-38-car
SMILES CC1C=CC=CC=CC=CC=CC=CC=CC(CC2C(C(CC(O2)(CC(CC(C(CCC(CC(CC(=O)OC(C(C1O)C)C)O)O)O)O)O)O)O)C(=O)O)OC3C(C(C(C(O3)C)O)N)O
View More Specs

Products 3
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAJ61491MC View Documents Alfa Aesar™
J61491MC
100mg Each for $78.96
 
AAJ6149103 View Documents Alfa Aesar™
J6149103
1g Each for $228.23
 
AAJ6149106 View Documents Alfa Aesar™
J6149106
5g Each for $974.62
 
Description

Description

Applications
Amphotericin B, antifungal activity has been used against leishmaniasis caused by protozoan parasites of the Leishmania genus. Amphotericin B trihydrate was observed to cause suppression of bone marrow progenitor cells and to induce Actinomycin D(CR001) sensitivity in drug resistant HELA cells in vitro.

Solubility
Soluble in aqueous buffers at pH 2.0 or 11.0. Insoluble at pH 6.0-7.0. Also soluble in DMSO or DMF

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
Specifications

Chemical Identifiers

1397-89-3
924.091
APKFDSVGJQXUKY-IYVSRKHGSA-N
(1S,3R,18S,19R,20R,21S,25R,27R,30R,31R,33S,35R,37S,38R)-3-[(2R,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-19,25,27,30,31,33,35,37-octahydroxy-18,20,21-trimethyl-23-oxo-22,39-dioxabicyclo[33.3.1]nonatriaconta-4,6,8,10,12,14,16-heptaene-38-car
C47H73NO17
MFCD00877763
134129663
CC1C=CC=CC=CC=CC=CC=CC=CC(CC2C(C(CC(O2)(CC(CC(C(CCC(CC(CC(=O)OC(C(C1O)C)C)O)O)O)O)O)O)O)C(=O)O)OC3C(C(C(C(O3)C)O)N)O

Specifications

1397-89-3
MFCD00877763
14,585
APKFDSVGJQXUKY-IYVSRKHGSA-N
(1S,3R,18S,19R,20R,21S,25R,27R,30R,31R,33S,35R,37S,38R)-3-[(2R,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-19,25,27,30,31,33,35,37-octahydroxy-18,20,21-trimethyl-23-oxo-22,39-dioxabicyclo[33.3.1]nonatriaconta-4,6,8,10,12,14,16-heptaene-38-car
134129663
Powder
100mg
Amphotericin B, Streptomyces nodosus
C47H73NO17
78342
Soluble in aqueous buffers at pH 2.0 or 11.0; Insoluble at pH 6.0-7.0; Also soluble in DMSO or DMF
CC1C=CC=CC=CC=CC=CC=CC=CC(CC2C(C(CC(O2)(CC(CC(C(CCC(CC(CC(=O)OC(C(C1O)C)C)O)O)O)O)O)O)O)C(=O)O)OC3C(C(C(C(O3)C)O)N)O
924.091
924.1
Yellow
Moisture and Light Sensitive
Safety and Handling

Safety and Handling

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

Warning

RTECSNumber : BU2625000

Recommended Storage : 2° to 8°C