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Thermo Scientific™ Lab Vision™ Amphiregulin Ab-2, Rabbit Polyclonal Antibody

Obtain accurate, reproducible results in western blotting and Immunoprecipitation experiments with Thermo Scientific™ Amphiregulin Ab-2, Rabbit Polyclonal Antibody.

$244.43 - $1,231.96

Specifications

Antigen Amphiregulin Ab-2
Concentration 1mg/mL
Applications Immunoprecipitation
Classification Polyclonal
Conjugate Unlabeled
View More Specs


Products ${productFamilyLength}
Catalog Number Mfr. No. Formulation Quantity Price Quantity  
Catalog Number Mfr. No. Formulation Quantity Price Quantity  
RB258P Thermo Scientific™ Lab Vision™
RB258P
Purified Ab with BSA and Azide 1mL Each for $1,121.67
RB258P0 Thermo Scientific™ Lab Vision™
RB258P0
Purified Ab with BSA and Azide 100μL Each for $244.43
RB258P1 Thermo Scientific™ Lab Vision™
RB258P1
Purified Ab with BSA and Azide 500μL Each for $744.39
RB258P1ABX Thermo Scientific™ Lab Vision™
RB258P1ABX
Ab without BSA/Azide (Frozen) 500μL Each for $818.92
RB258PABX Thermo Scientific™ Lab Vision™
RB258PABX
Ab without BSA/Azide (Frozen) 1mL Each for $1,231.96
Specifications

Description

Obtain accurate, reproducible results in western blotting and immunoprecipitation experiments with Thermo Scientific™ Amphiregulin Ab-2, Rabbit Polyclonal Antibody.

 

Amphiregulin (AR) binds to EGF-Receptor (EGFR) with lower affinity than EGF. The mature secreted form AR is an 84-amino acid residue glycosylated polypeptide growth regulator, which is generated by proteolytic processing of a 252-amino acid transmembrane precursor. Seven different polypeptide ligands, which derive from distinct genes, are capable of binding to the extracellular domain of EGFR. These ligands include EGF, TGFα, AR, HB-EGF, cripto-1, epiregulin, and βcellulin. All of these growth factors contain a characteristic EGF-like domain which is defined by 6 evenly spaced cysteine residues that generate 3 loops through the formation of disulfide bonds. AR protein has been localized by immunohistochemistry to the epithelium of the colon, stomach, pancreas, breast, and placenta. AR is reportedly overexpressed in human cancers of breast, colon, stomach, and pancreas.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human and Mouse. Others not tested.

Epitope: aa 26-44

Immunogen: A synthetic 19-mer peptide, corresponding to aa 26-44 from the secreted amphiregulin of human origin

Molecular Weight: 18.5-22.5kDa

Positive Control: HT29, LS174T cells

Cellular Localization: Cytoplasmic and/or nuclear

Recommended for:

  • Western Blotting
  • Immunoprecipitation (Native verified)

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

Amphiregulin Ab-2
Immunoprecipitation
Unlabeled
Concentrated
RUO
Primary
IgG
1mg/mL
Polyclonal
Human,Mouse
Rabbit
EGFR Family
A synthetic 19-mer peptide, corresponding to aa 26-44 from the secreted amphiregulin of human origin