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alpha GalCer:CD1d complex Mouse anti-Mouse, PE, Clone: L363, eBioscience™

Mouse Monoclonal Antibody

$143.55 - $419.05

Specifications

Antigen alpha GalCer:CD1d complex
Clone L363
Host Species Mouse
Gene Alias alpha GalCer-CD1d complex, alphaGalCerCD1d complex, alpha galcer-CD1d complex, alpha-galactosylceramide, alpha galactosylceramide, CD1d
Species Reactivity Mouse
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 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5010714

 
affymetrix
12201980
25μg Each for $143.55

5010715

 
affymetrix
12201982
100μg Each for $419.05
Description & Specifications

Specifications

Antigen alpha GalCer:CD1d complex
Clone L363
Host Species Mouse
Gene Alias alpha GalCer-CD1d complex, alphaGalCerCD1d complex, alpha galcer-CD1d complex, alpha-galactosylceramide, alpha galactosylceramide, CD1d
Species Reactivity Mouse
Applications Flow Cytometry
Regulatory Status RUO
Conjugate PE
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.2mg/mL

This L363 monoclonal antibody reacts with α-galactosylceramide bound to the mouse MHC class I-like protein CD1d. This complex is recognized by invariant natural killer T (iNKT) cells, a subset of T lymphocytes that expresses the invariant TCR α chain Vα14Jα18. Activation of iNKT cells leads to production of Th1 and Th2-associated cytokines as well as dendritic cell maturation.

The L363 antibody has been reported to neutralize iNKT cell activation by α-galactosylceramide:CD1d complexes.