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alpha GalCer:CD1d complex Mouse anti-Mouse, Clone: L363, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

$129.05 - $245.05

Specifications

Antigen alpha GalCer:CD1d complex
Clone L363
Host Species Mouse
Gene Alias alpha GalCer-CD1d complex
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5014499

 
affymetrix
16-2019-80
25μg Each for $129.05

5014500

 
affymetrix
16201982
100μg Each for $245.05
Description & Specifications

Specifications

Antigen alpha GalCer:CD1d complex
Clone L363
Host Species Mouse
Gene Alias alpha GalCer-CD1d complex
Species Reactivity Mouse
Applications Flow Cytometry
Applications Functional Assay
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, no sodium azide
Concentration 1mg/mL

This L363 monoclonal antibody reacts with α-galactosylceramide bound to the mouse MHC class I-like protein CD1d. This complex is recognized by invariant natural killer T (iNKT) cells, a subset of T lymphocytes that expresses the invariant TCR α chain Vα14Jα18. Activation of iNKT cells leads to production of Th1 and Th2-associated cytokines as well as dendritic cell maturation.

The L363 antibody has been reported to neutralize iNKT cell activation by α-galactosylceramide:CD1d complexes.