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The L363 antibody has been reported to neutralize iNKT cell activation by α-galactosylceramide:CD1d complexes.Description & Specifications
DescriptionThis L363 monoclonal antibody reacts with α-galactosylceramide bound to the mouse MHC class I-like protein CD1d. This complex is recognized by invariant natural killer T (iNKT) cells, a subset of T lymphocytes that expresses the invariant TCR α chain Vα14Jα18. Activation of iNKT cells leads to production of Th1 and Th2-associated cytokines as well as dendritic cell maturation.
The L363 antibody has been reported to neutralize iNKT cell activation by α-galactosylceramide:CD1d complexes.
|alpha GalCer:CD1d complex|
|aqueous buffer, no sodium azide|
|alpha GalCer-CD1d complex|
|Flow Cytometry,Functional Assay|
|Store at 2-8°C.|