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Alpha Catenin Mouse anti-Human, Clone: 1G5, eBioscience™

Mouse Monoclonal Antibody

$146.45 - $146.45

Specifications

Antigen Alpha Catenin
Clone 1G5
Host Species Murine
Species Reactivity Human
Applications Flow Cytometry,Immunocytochemistry,Immunohistochemistry (Formalin/Paraffin),Immunoprecipitation,Western Blot
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Disclaimers:

For Research Use Only.



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Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501122770 Life Technologies
LS14912080
25μg Each for $146.45
Specifications

Description

The monoclonal antibody 1G5 recognizes human alpha catenin. Alpha catenin plays a role in cell-cell adhesion through its function in the binding and bundling of actin. The N-terminus of alpha catenin binds beta catenin and the C-terminus binds actin. Monomeric alpha catenin acts as a physical linker between the cadherin-beta catenin complex and the actin cytoskeleton and is stabilized by dimeric alpha catenin found in the cytoplasm. Alpha catenin also binds other actin-related proteins, including vinculin, alpha-actinin, ZO-1, afadin, formin-1, and Rho. Alpha catenin is absent in some tumor cell lines and reduced in some human carcinomas.
Description & Specifications

Specifications

Alpha Catenin
Murine
Flow Cytometry,Immunocytochemistry,Immunohistochemistry (Formalin/Paraffin),Immunoprecipitation,Western Blot
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL
1G5
Human
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer