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Alpha Catenin Mouse anti-Human, Clone: 1G5, eBioscience™

Mouse Monoclonal Antibody

$143.55 - $346.55

Specifications

Antigen Alpha Catenin
Clone 1G5
Host Species Mouse
Species Reactivity Human
Applications Flow Cytometry
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501122770

 
affymetrix
14912080
25μg Each for $143.55

501122771

 
affymetrix
14912082
100μg Each for $346.55
Description & Specifications

Specifications

Antigen Alpha Catenin
Clone 1G5
Host Species Mouse
Species Reactivity Human
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The monoclonal antibody 1G5 recognizes human alpha catenin. Alpha catenin plays a role in cell-cell adhesion through its function in the binding and bundling of actin. The N-terminus of alpha catenin binds beta catenin and the C-terminus binds actin. Monomeric alpha catenin acts as a physical linker between the cadherin-beta catenin complex and the actin cytoskeleton and is stabilized by dimeric alpha catenin found in the cytoplasm. Alpha catenin also binds other actin-related proteins, including vinculin, alpha-actinin, ZO-1, afadin, formin-1, and Rho. Alpha catenin is absent in some tumor cell lines and reduced in some human carcinomas.