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Alendronate sodium trihydrate, 97%, Thermo Scientific Chemicals
$77.16 - $298.27
Chemical Identifiers
| CAS | 121268-17-5 |
|---|---|
| Molecular Formula | C4H18NNaO10P2 |
| Molecular Weight (g/mol) | 325.122 |
| MDL Number | MFCD01748233 |
| InChI Key | DCSBSVSZJRSITC-UHFFFAOYSA-M |
| Synonym | alendronate sodium hydrate, alendronate sodium trihydrate, alendronate sodium, alendronate monosodium trihydrate, alendros, adronat, fosamax, sodium alendronate hydrate, elandor, fosalan |
| PubChem CID | 23681107 |
| ChEBI | CHEBI:2566 |
| IUPAC Name | sodium;(4-amino-1-hydroxy-1-phosphonobutyl)-hydroxyphosphinate;trihydrate |
| SMILES | C(CC(O)(P(=O)(O)O)P(=O)(O)[O-])CN.O.O.O.[Na+] |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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AAJ6139703
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Thermo Scientific Chemicals
J6139703 |
1 g |
Each for $77.16
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AAJ6139706
|
Thermo Scientific Chemicals
J6139706 |
5 g |
Each for $298.27
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Description
Alendronate sodium trihydrate is used as a bone resorption inhibitor, farnesyl diphosphate synthase inhibitor and CD45 protein tyrosine phosphatase inhibitor. A robust inhibitor of bone resorption that induces apoptosis. Alendronate inhibits the migration and invasion of PC-3 cells (sc-2220) by interfering with the mevalonate pathway. Additionally, Alendronate, Sodium Salt is an inhibitor of CD45RC and MMP.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsAlendronate sodium trihydrate is used as a bone resorption inhibitor, farnesyl diphosphate synthase inhibitor and CD45 protein tyrosine phosphatase inhibitor. A robust inhibitor of bone resorption that induces apoptosis. Alendronate inhibits the migration and invasion of PC-3 cells (sc-2220) by interfering with the mevalonate pathway. Additionally, Alendronate, Sodium Salt is an inhibitor of CD45RC and MMP.
Solubility
Soluble in water at 10mg/ml
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Keep away from strong oxidizing agents.
Chemical Identifiers
| 121268-17-5 | |
| 325.122 | |
| DCSBSVSZJRSITC-UHFFFAOYSA-M | |
| 23681107 | |
| sodium;(4-amino-1-hydroxy-1-phosphonobutyl)-hydroxyphosphinate;trihydrate |
| C4H18NNaO10P2 | |
| MFCD01748233 | |
| alendronate sodium hydrate, alendronate sodium trihydrate, alendronate sodium, alendronate monosodium trihydrate, alendros, adronat, fosamax, sodium alendronate hydrate, elandor, fosalan | |
| CHEBI:2566 | |
| C(CC(O)(P(=O)(O)O)P(=O)(O)[O-])CN.O.O.O.[Na+] |
Specifications
| 121268-17-5 | |
| C4H18NNaO10P2 | |
| 1 g | |
| alendronate sodium hydrate, alendronate sodium trihydrate, alendronate sodium, alendronate monosodium trihydrate, alendros, adronat, fosamax, sodium alendronate hydrate, elandor, fosalan | |
| DCSBSVSZJRSITC-UHFFFAOYSA-M | |
| sodium;(4-amino-1-hydroxy-1-phosphonobutyl)-hydroxyphosphinate;trihydrate | |
| 23681107 | |
| 325.12 (271.08 Anhydrous) | |
| Solid |
| White | |
| MFCD01748233 | |
| 14,229 | |
| Soluble in water at 10mg/ml | |
| C(CC(O)(P(=O)(O)O)P(=O)(O)[O-])CN.O.O.O.[Na+] | |
| 325.122 | |
| CHEBI:2566 | |
| 97% | |
| Alendronate sodium trihydrate |
Safety and Handling
GHS H Statement
H302
Harmful if swallowed.
P264b-P270-P301+P312-P330-P501c
H302
RTECSNumber : SZ6523500
TSCA : No
Recommended Storage : Store at -20°C
RUO – Research Use Only