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Thermo Scientific™ Lab Vision™ Adenovirus Type 5 E1A Ab-1, Mouse Monoclonal Antibody


Obtain accurate, reproducible results in immunohistochemistry, western blotting, immunofluorescence, and immunoprecipitation experiments.

Manufacturer: thermo scientific™ lab vision™  MS587P1ABX

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Catalog No. MS587P1ABX

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Description & Specifications

Specifications

Antigen Adenovirus Type 5 E1A Ab-1
Applications Immunofluorescence
Applications Immunoprecipitation
Applications Western Blotting
Classification Monoclonal
Clone M58
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Adenovirus
Format Concentrated
Host Species Mouse
Immunogen Adenovirus
Isotype IgG2a kappa
Quantity 100µL
Regulatory Status RUO
Research Discipline Infectious Disease
Type Primary

Obtain accurate, reproducible results in immunohistochemistry, western blotting, immunofluorescence, and immunoprecipitation experiments with Thermo Scientific™ Adenovirus Type 5 E1A Ab-1, Mouse Monoclonal Antibody.

 

The early region (E1A) of the adenovirus genome plays a central role in cellular transformation and regulation of gene expression. The E1A region encodes a series of related proteins (35-46kDa) with multifuctional capabilities that form a specific complex with the retinoblastoma tumor suppressor gene product (Rb protein). The E1A and E1B regions together comprise the transforming region of adenovirus. While expression of E1A alone is sufficient to immortalize primary cells, complete transformation requires the additional expression of the E1B region. Several conserved regions of E1A are similar to portions of other viral oncoproteins like the HPV-16 and HPV-18 E7 and SV40 large T antigen.

Host Species: Mouse

Clone: M58

Isotype: IgG2a/κ

Species Reactivity: Adenovirus.

Immunogen: Adenovirus

Molecular Weight: 35-46kDa

Positive Control: 293 cells or adenovirus infected cells and tissues

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native verified)

Note:

USA: RUO; Int'l: RUO