Please login to your online account to display your discounted pricing

Alfa Aesar™ Actinomycin D

$118.73 - $118.73

Chemical Identifiers

Chemical Name or Material Actinomycin D
CAS 50-76-0
Formula Weight 1255.4
MDL Number MFCD00005033
UN Number UN3462
Beilstein 605235
Merck Index 14,2800
Synonym Dactinomycin; Actinomycin C1
View More Specs
Products
Catalog Number Mfr. No. Quantity Price Quantity    

AAJ60148LB0

  SDS
alfa aesar™
J60148LB0
5mg Each for $118.73
Description & Specifications

Specifications

Melting Point 251° to 253°C
Formula Weight 1255.4
Chemical Name or Material Actinomycin D
Health Hazard 2 GHS H Statement
H300-H360-H351
Fatal if swallowed.
May damage fertility or the unborn child.
Suspected of causing cancer.
RTECS Number AU1575000
MDL Number MFCD00005033
Merck Index 14,2800
Color Orange to red
CAS 50-76-0
Synonym Dactinomycin; Actinomycin C1
Health Hazard 3 GHS P Statement
P281-P301+P310-P308+P313-P321-P405-P501a
Use personal protective equipment as required.
IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
IF exposed or concerned: Get medical advice/attention.
Specific treatment (see label).
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
DOT Information Transport Hazard Class: 6.1; Packaging Group: II; Proper Shipping Name: TOXINS, EXTRACTED FROM LIVING SOURCES, SOLID, N.O.S.
Health Hazard 1 Danger
Physical Form Powder
UN Number UN3462
Beilstein 605235
Storage Note 1 -30° to -10°C
Quantity 5mg

Applications
Actinomycin D is used as an anti-neoplastic antibiotic. It is also used to inhibit RNA polymerase and is a potent inducer of apoptosis. It is also used as a potent antibiotic that binds to the GpC steps of DNA. Inhibits DNA-primed RNA polymerase by complexing with DNA via deoxyguanosine residues. A DNA-intercalator with growth inhibitory activity against certain leukemias and sarcomas. At higher concentrations, DNA polymerase is inhibited. Inhibits cell growth and colony formation in synchronized HeLa cells.

Solubility
It is soluble ino 50 mM in DMSO.

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.

Safety and Handling

Danger

GHS P Statement
P281-P301+P310-P308+P313-P321-P405-P501a
Use personal protective equipment as required.
IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
IF exposed or concerned: Get medical advice/attention.
Specific treatment (see label).
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

GHS H Statement
H300-H360-H351
Fatal if swallowed.
May damage fertility or the unborn child.
Suspected of causing cancer.

-30° to -10°C