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Alfa Aesar™ Actinomycin D

$121.30 - $121.30

Chemical Identifiers

CAS 50-76-0
Formula Weight 1255.4
MDL Number MFCD00005033
UN Number UN3462
Beilstein 605235
Merck Index 14,2800
Synonym Dactinomycin; Actinomycin C1
Chemical Name or Material Actinomycin D
View More Specs


Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAJ60148LB0 SDS Alfa Aesar™
J60148LB0
5mg Each for $121.30
Specifications

Description

Applications
Actinomycin D is used as an anti-neoplastic antibiotic. It is also used to inhibit RNA polymerase and is a potent inducer of apoptosis. It is also used as a potent antibiotic that binds to the GpC steps of DNA. Inhibits DNA-primed RNA polymerase by complexing with DNA via deoxyguanosine residues. A DNA-intercalator with growth inhibitory activity against certain leukemias and sarcomas. At higher concentrations, DNA polymerase is inhibited. Inhibits cell growth and colony formation in synchronized HeLa cells.

Solubility
It is soluble ino 50 mM in DMSO.

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
Description & Specifications

Chemical Identifiers

50-76-0
MFCD00005033
605235
Dactinomycin; Actinomycin C1
1255.4
UN3462
14,2800
Actinomycin D

Specifications

50-76-0
1255.4
UN3462
14,2800
Orange to red
5mg
Powder
MFCD00005033
605235
Dactinomycin; Actinomycin C1
251° to 253°C
Actinomycin D

Safety and Handling

GHS H Statement
H300-H360-H351
Fatal if swallowed.
May damage fertility or the unborn child.
Suspected of causing cancer.

GHS P Statement
P281-P301+P310-P308+P313-P321-P405-P501a
Use personal protective equipment as required.
IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
IF exposed or concerned: Get medical advice/attention.
Specific treatment (see label).
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

Danger

DOTInformation : Transport Hazard Class: 6.1; Packaging Group: II; Proper Shipping Name: TOXINS, EXTRACTED FROM LIVING SOURCES, SOLID, N.O.S.

RTECSNumber : AU1575000

storageNote1 : -30° to -10°C