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Tocris™ ABT 724 trihydrochloride

Potent, selective D4 partial agonist; proerectile

$191.50 - $808.39

Specifications

Product Type ABT 724 trihydrochloride
Inhibitors ABT 724 trihydrochloride
Molecular Weight 402.75
Purity >99
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 Disclaimers

For Research Use Only

Products
Catalog Number Mfr. No. Quantity Price Quantity    

221410

 
tocris™
2214/10
10mg Each for $191.50

221450

 
tocris™
2214/50
50mg Each for $808.39
Description & Specifications

Specifications

Product Type ABT 724 trihydrochloride
Inhibitors ABT 724 trihydrochloride
Molecular Weight 402.75
Purity >99

Potent dopamine D4 receptor partial agonist (EC50 = 12.4 nM; 61% efficacy vs. dopamine). Has no agonist activity at D2 receptors (EC50 > 10μM). Selective in rats in vivo; produces penile erection following i.c.v. administration; increases intracavernosal pressure and potentiates the proerectile effects of sildenafil following s.c. administration. Displays minimal side effects.

  • Chemical Name: 2-[[4-(2-Pyridinyl)-1-piperazinyl]methyl]-1H-benzimidazole trihydrochloride
  • Formula: C17H19N5.3HCl
  • CAS Number: 587870-77-7
  • Solubility: Soluble to 100mM in water
  • Purity: >99