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ABL1 [E255K] Recombinant Human Protein, Invitrogen™ DFS Item

ABL1 [E255K] Recombinant Human Protein

Manufacturer:  Life Technologies LSPV3864

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Catalog No. PV3864



Description

Description

The ABL1 proto-oncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. The E255K mutant is a Gleevec resistant form of ABL1.
Specifications

Specifications

NP_005148.2, E255K
Pharma and biopharma, protein assays and analysis, target and lead identification and validation
125.4kDa
50% by SDS-PAGE
–80°C
1 Each
ABL1 E255K, ABL, c-ABL
ABL1 E225K was pre-diluted in enzyme dilution buffer and assayed in 50mM Tris (pH 7.5), 10mM MgCl2, 1mM DTT, 0.01% NP-40, 200μM ATP, 333μg/mL Abl1 peptide substrate (EAIYAAPFAKKK) and trace [32P]-γ-ATP for 10 minutes at 30°C
Kinase and inhibitors
ABL
ABL1 [E255K] Recombinant Human Protein
Human
0.35mg/mL
25, 7376
ABL1 [E255K] Recombinant Human Protein
10μg
For research use only. Not for use in diagnostic procedures
Cytoplasmic tyrosine kinase
ABL1 [E255K] Recombinant Human Protein
Kinase assay
Baculovirus
E255K
490nmoles of phosphate transferred to Abl1 peptide substrate (EAIYAAPFAKKK) per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 1.67μg/mL
His Tag
Documents

For Research Use Only. Not for use in diagnostic procedures.